Cellular phenotype database
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General Information
DescriptionA repository for systems microscopy data
Homepagehttp://www.ebi.ac.uk/fg/sym
Publications
Cellular phenotype database: a repository for systems microscopy data
Catherine Kirsanova; Alvis Brazma; Gabriella Rustici; Ugis Sarkans
Motivation: The Cellular Phenotype Database (CPD) is a repository for data derived from high-throughput systems microscopy studies. The aims of this resource are: (i) to provide easy access to cellular phenotype and molecular localization data for the broader research community; (ii) to facilitate integration of independent phenotypic studies by means of data aggregation techniques, including use of an ontology and (iii) to facilitate development of analytical methods in this field.
Results: In this article we present CPD, its data structure and user interface, propose a minimal set of information describing RNA interference experiments, and suggest a generic schema for management and aggregation of outputs from phenotypic or molecular localization experiments. The database has a flexible structure for management of data from heterogeneous sources of systems microscopy experimental outputs generated by a variety of protocols and technologies and can be queried by gene, reagent, gene attribute, study keywords, phenotype or ontology terms.
Availability and implementation: CPD is developed as part of the Systems Microscopy Network of Excellence and is accessible at http://www.ebi.ac.uk/fg/sym.
Contact: jes@ebi.ac.uk or ugis@ebi.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
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