General Information
| Description | Benchmarking protein structures by docking under AFM topographs |
| Homepage | http://biodev.cea.fr/dockafm |
Publications
DockAFM: benchmarking protein structures by docking under AFM topographs
Summary:
Proteins can adopt a variety of conformations. We present a simple server for scoring the agreement between 3D atomic structures and experimental envelopes obtained by atomic force microscopy. Three different structures of immunoglobulins (IgG) or blood coagulation factor V activated were tested and their agreement with several topographical surfaces was computed. This approach can be used to test structural variability within a family of proteins.
Availability and implementation:
DockAFM is available at http://biodev.cea.fr/dockafm.
Contact:
chaves.rui.c@gmail.com or jlpellequer@cea.fr
Supplementary information:
Supplementary data are available at Bioinformatics online.
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