DockAFM
Computational Tool
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General Information
DescriptionBenchmarking protein structures by docking under AFM topographs
Homepagehttp://biodev.cea.fr/dockafm
Publications
DockAFM: benchmarking protein structures by docking under AFM topographs
Rui C. Chaves; Jean-Luc Pellequer
Summary: Proteins can adopt a variety of conformations. We present a simple server for scoring the agreement between 3D atomic structures and experimental envelopes obtained by atomic force microscopy. Three different structures of immunoglobulins (IgG) or blood coagulation factor V activated were tested and their agreement with several topographical surfaces was computed. This approach can be used to test structural variability within a family of proteins.
Availability and implementation: DockAFM is available at http://biodev.cea.fr/dockafm.
Contact: chaves.rui.c@gmail.com or jlpellequer@cea.fr
Supplementary information: Supplementary data are available at Bioinformatics online.
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