General Information
| Description | Analyzing protein networks to predict enzymatic function and substrates in Cytoscape |
| Homepage | http://mammoth.bcm.tmc.edu/networks/ |
Publications
ETAscape: analyzing protein networks to predict enzymatic function and substrates in Cytoscape
Summary:
Most proteins lack experimentally validated functions. To address this problem, we implemented the Evolutionary Trace Annotation (ETA) method in the Cytoscape network visualization environment. The result is the ETAscape plugin, which builds a structural genomics network based on local structural and evolutionary similarities among proteins and then globally diffuses known annotations across the resulting network. The plugin displays these novel functional annotations, their confidence, the molecular basis for individual matches and the set of matches that lead to a prediction.
Availability:
The ETA Network Plugin is available publicly for download at http://mammoth.bcm.tmc.edu/networks/.
Contact:
lichtarge@bcm.edu
Related Tools
CyClus3D
Published April 2011
A Cytoscape plugin for clustering network motifs in integrated networks
GALANT
Published July 2013
A Cytoscape plugin for visualizing data as functional landscapes projected onto biological networks
SiPAN
Published March 2015
Simultaneous prediction and alignment of protein–protein interaction networks
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
