General Information
| Description | Web-based integration of GWAS results with biological annotations |
| Homepage | http://enlight.usc.edu |
Publications
Enlight: web-based integration of GWAS results with biological annotations
Summary:
Identifying causal variants remains a key challenge in post-GWAS (genome-wide association study) era, as many GWAS single-nucleotide polymorphisms (SNPs) (including imputed ones) fall into non-coding regions, making it difficult to associate statistical significance with predicted functionality. Therefore, we created a web-based tool, Enlight, which overlays functional annotation information, such as histone modification states, methylation patterns, transcription factor binding sites, eQTL and higher-order chromosomal structure, to GWAS results.
Availability and implementation:
Accessible by a Web browser at http://enlight.usc.edu .
Contact:
kaiwang@usc.edu
Related Tools
GRASP
Published June 2014
Analysis of genotype–phenotype results from 1390 genome-wide association studies and corresponding open access database
PANOGA
Published January 2014
A web server for identification of SNP-targeted pathways from genome-wide association study data
JEPEG
Published December 2014
A summary statistics based tool for gene-level joint testing of functional variants
GERV
Published October 2015
A statistical method for generative evaluation of regulatory variants for transcription factor binding
GenoWAP
Published October 2015
GWAS signal prioritization through integrated analysis of genomic functional annotation
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
