General Information
| Description | Gene prioritization for RNAi screens |
| Homepage | http://funl.org |
Publications
FUN-L: gene prioritization for RNAi screens
Motivation:
Most biological processes remain only partially characterized with many components still to be identified. Given that a whole genome can usually not be tested in a functional assay, identifying the genes most likely to be of interest is of critical importance to avoid wasting resources.
Results:
Given a set of known functionally related genes and using a state-of-the-art approach to data integration and mining, our Functional Lists (FUN-L) method provides a ranked list of candidate genes for testing. Validation of predictions from FUN-L with independent RNAi screens confirms that FUN-L-produced lists are enriched in genes with the expected phenotypes. In this article, we describe a website front end to FUN-L.
Availability and implementation:
The website is freely available to use at http://funl.org
Contact:
ucbcjle@live.ucl.ac.uk
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