GO-Module
Computational Tool
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General Information
DescriptionFunctional synthesis and improved interpretation of Gene Ontology patterns
Homepagehttp://lussierlab.org/GO-Module
Publications
GO-Module: functional synthesis and improved interpretation of Gene Ontology patterns
Xinan Yang; Jianrong Li; Younghee Lee; Yves A. Lussier
Summary: GO-Module is a web-accessible synthesis and visualization tool developed for end-user biologists to greatly simplify the interpretation of prioritized Gene Ontology (GO) terms. GO-Module radically reduces the complexity of raw GO results into compact biomodules in two distinct ways, by (i) constructing biomodules from significant GO terms based on hierarchical knowledge, and (ii) refining the GO terms in each biomodule to contain only true positive results. Altogether, the features (biomodules) of GO-Module outputs are better organized and on average four times smaller than the input GO terms list (P = 0.0005, n = 16).
Availability: http://lussierlab.org/GO-Module
Contact: ylussier@bsd.uchicago.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
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