GlycoProfileAssigner
Computational Tool
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General Information
DescriptionAutomated structural assignment with error estimation for glycan LC data
Homepagehttps://bitbucket.org/fergaljd/glycoprofileassigner
Publications
GlycoProfileAssigner: automated structural assignment with error estimation for glycan LC data
Fergal J. Duffy; Pauline M. Rudd
Motivation: Sequencing glycan structures is a difficult problem that requires the use of multiple experimental approaches. One powerful approach to glycan sequencing is the combination of liquid chromatography with sequential exoglycosidase digestions; however, interpreting this can be difficult and time-consuming. To aid this process, we introduce GlycoProfileAssigner, software for automated structural assignment of glycan profile data from liquid chromatography experiments.
Results : GlycoProfileAssigner has been tested on human IgG data, and can retrieve the correct structure in 14 out of 16 peaks tested.
Availability and Implementation: The programme and its source code is available at https://bitbucket.org/fergaljd/glycoprofileassigner
Contact : pauline.rudd@nibrt.ie
Supplementary information: Supplementary data are available at Bioinformatics online.
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