General Information
| Description | Identifying clinically and phenotypically significant network modules with disease mutations for biomarker discovery |
| Homepage | http://www.baderlab.org/Sofware/HyperModules |
Publications
HyperModules: identifying clinically and phenotypically significant network modules with disease mutations for biomarker discovery
Summary:
Correlating disease mutations with clinical and phenotypic information such as drug response or patient survival is an important goal of personalized cancer genomics and a first step in biomarker discovery. HyperModules is a network search algorithm that finds frequently mutated gene modules with significant clinical or phenotypic signatures from biomolecular interaction networks.
Availability and implementation:
HyperModules is available in Cytoscape App Store and as a command line tool at www.baderlab.org/Sofware/HyperModules .
Contact:
Juri.Reimand@utoronto.ca or Gary.Bader@utoronto.ca
Supplementary information:
Supplementary data are available at Bioinformatics online
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