IMA
Computational Tool
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General Information
DescriptionAn R package for high-throughput analysis of Illumina's 450K Infinium methylation data
Homepagehttp://www.rforge.net/IMA
Publications
IMA: an R package for high-throughput analysis of Illumina's 450K Infinium methylation data
Dan Wang; Li Yan; Qiang Hu; Lara E. Sucheston; Michael J. Higgins; Christine B. Ambrosone; Candace S. Johnson; Dominic J. Smiraglia; Song Liu
Summary: The Illumina Infinium HumanMethylation450 BeadChip is a newly designed high-density microarray for quantifying the methylation level of over 450 000 CpG sites within human genome. Illumina Methylation Analyzer (IMA) is a computational package designed to automate the pipeline for exploratory analysis and summarization of site-level and region-level methylation changes in epigenetic studies utilizing the 450K DNA methylation microarray. The pipeline loads the data from Illumina platform and provides user-customized functions commonly required to perform exploratory methylation analysis for individual sites as well as annotated regions.
Availability: IMA is implemented in the R language and is freely available from http://www.rforge.net/IMA.
Contact: song.liu@roswellpark.org
DOI: https://doi.org/10.1093/bioinformatics/bts013
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