INstruct
Computational Tool
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General Information
DescriptionA database of high-quality 3D structurally resolved protein interactome networks
Homepagehttp://instruct.yulab.org
Publications
INstruct: a database of high-quality 3D structurally resolved protein interactome networks
Michael J. Meyer; Jishnu Das; Xiujuan Wang; Haiyuan Yu
Summary: INstruct is a database of high-quality, 3D, structurally resolved protein interactome networks in human and six model organisms. INstruct combines the scale of available high-quality binary protein interaction data with the specificity of atomic-resolution structural information derived from co-crystal evidence using a tested interaction interface inference method. Its web interface is designed to allow for flexible search based on standard and organism-specific protein and gene-naming conventions, visualization of protein architecture highlighting interaction interfaces and viewing and downloading custom 3D structurally resolved interactome datasets.
Availability: INstruct is freely available on the web at http://instruct.yulab.org with all major browsers supported.
Contact: haiyuan.yu@cornell.edu
Supplementary information: Supplementary data are available at Bioinformatics online.
Metrics:
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