General Information
| Description | A Cytoscape plugin for gene set enrichment and topological analysis based on interaction networks |
| Homepage | http://apps.cytoscape.org/apps/jepetto |
Publications
JEPETTO: a Cytoscape plugin for gene set enrichment and topological analysis based on interaction networks
Summary:
JEPETTO (Java Enrichment of Pathways Extended To TOpology) is a Cytoscape 3.x plugin performing integrative human gene set analysis. It identifies functional associations between genes and known cellular pathways, and processes using protein interaction networks and topological analysis. The plugin integrates information from three separate web servers we published previously, specializing in enrichment analysis, pathways expansion and topological matching. This integration substantially simplifies the analysis of user gene sets and the interpretation of the results. We demonstrate the utility of the JEPETTO plugin on a set of misregulated genes associated with Alzheimer’s disease.
Availability:
Source code and binaries are freely available for download at http://apps.cytoscape.org/apps/jepetto, implemented in Java and multi-platform. Installable directly via Cytoscape plugin manager. Released under the GNU General Public Licence.
Contact:
jepetto.plugin@gmail.com
Supplementary information:
Supplementary data are available at Bioinformatics online.
Related Tools
CytoscapeRPC
Published June 2011
A plugin to create, modify and query Cytoscape networks from scripting languages
CluePedia Cytoscape plugin
Published January 2013
Pathway insights using integrated experimental and in silico data
P
Published August 2014
Cytoscape app for protein complex expansion using protein–protein interaction networks
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
