General Information
| Description | An R/bioconductor package to predict regulatory sequences using support vector machines |
| Homepage | https://github.com/aitgon/LedPred |
Publications
LedPred: an R/bioconductor package to predict regulatory sequences using support vector machines
Summary:
Supervised classification based on support vector machines (SVMs) has successfully been used for the prediction of cis-regulatory modules (CRMs). However, no integrated tool using such heterogeneous data as position-specific scoring matrices, ChIP-seq data or conservation scores is currently available. Here, we present LedPred, a flexible SVM workflow that predicts new regulatory sequences based on the annotation of known CRMs, which are associated to a large variety of feature types. LedPred is provided as an R/Bioconductor package connected to an online server to avoid installation of non-R software. Due to the heterogeneous CRM feature integration, LedPred excels at the prediction of regulatory sequences in Drosophila and mouse datasets compared with similar SVM-based software.
Availability and implementation:
LedPred is available on GitHub: https://github.com/aitgon/LedPred and Bioconductor: http://bioconductor.org/packages/release/bioc/html/LedPred.html under the MIT license.
Contact:
aitor.gonzalez@univ-amu.fr
Supplementary information:
Supplementary data are available at Bioinformatics online.
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
