General Information
| Description | An efficient tool for de novo peptide sequencing utilizing the hadoop distributed computing framework |
| Homepage | http://bioinfo.hupo.org.cn/MRUniNovo/index.php |
Publications
MRUniNovo: an efficient tool for de novo peptide sequencing utilizing the hadoop distributed computing framework
Summary:
Tandem mass spectrometry-based de novo peptide sequencing is a complex and time-consuming process. The current algorithms for de novo peptide sequencing cannot rapidly and thoroughly process large mass spectrometry datasets. In this paper, we propose MRUniNovo, a novel tool for parallel de novo peptide sequencing. MRUniNovo parallelizes UniNovo based on the Hadoop compute platform. Our experimental results demonstrate that MRUniNovo significantly reduces the computation time of de novo peptide sequencing without sacrificing the correctness and accuracy of the results, and thus can process very large datasets that UniNovo cannot.
Availability and Implementation
: MRUniNovo is an open source software tool implemented in java. The source code and the parameter settings are available at http://bioinfo.hupo.org.cn/MRUniNovo/index.php
Contact:
s131020002@hnu.edu.cn; taochen1019@163.com
Supplementary information:
Supplementary data are available at Bioinformatics online.
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