MetaboSignal
Computational Tool
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General Information
DescriptionA network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
Homepagehttps://bioconductor.org/packages/MetaboSignal/
Publications
MetaboSignal: a network-based approach for topological analysis of metabotype regulation via metabolic and signaling pathways
Andrea Rodriguez-Martinez; Rafael Ayala; Joram M. Posma; Ana L. Neves; Dominique Gauguier; Jeremy K. Nicholson; Marc-Emmanuel Dumas
Summary: MetaboSignal is an R package that allows merging metabolic and signaling pathways reported in the Kyoto Encyclopaedia of Genes and Genomes (KEGG). It is a network-based approach designed to navigate through topological relationships between genes (signaling- or metabolic-genes) and metabolites, representing a powerful tool to investigate the genetic landscape of metabolic phenotypes.
Availability and Implementation: MetaboSignal is available from Bioconductor: https://bioconductor.org/packages/MetaboSignal/
Contact: m.dumas@imperial.ac.uk.
Supplementary information: Supplementary data are available at Bioinformatics online.
DOI: https://doi.org/10.1093/bioinformatics/btw697
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