Metingear
Computational Tool
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General Information
DescriptionA development environment for annotating genome-scale metabolic models
Homepagehttp://johnmay.github.com/metingear
Publications
Metingear: a development environment for annotating genome-scale metabolic models
John W. May; A. Gordon James; Christoph Steinbeck
Summary: Genome-scale metabolic models often lack annotations that would allow them to be used for further analysis. Previous efforts have focused on associating metabolites in the model with a cross reference, but this can be problematic if the reference is not freely available, multiple resources are used or the metabolite is added from a literature review. Associating each metabolite with chemical structure provides unambiguous identification of the components and a more detailed view of the metabolism. We have developed an open-source desktop application that simplifies the process of adding database cross references and chemical structures to genome-scale metabolic models. Annotated models can be exported to the Systems Biology Markup Language open interchange format.
Availability: Source code, binaries, documentation and tutorials are freely available at http://johnmay.github.com/metingear. The application is implemented in Java with bundles available for MS Windows and Macintosh OS X.
Contact: johnmay@ebi.ac.uk
Supplementary information: Supplementary data are available at Bioinformatics online.
DOI: https://doi.org/10.1093/bioinformatics/btt342
Metrics:
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