NBC
Computational Tool
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General Information
DescriptionThe Naïve Bayes Classification tool webserver for taxonomic classification of metagenomic reads
Homepagehttp://nbc.ece.drexel.edu
Publications
NBC: the Naïve Bayes Classification tool webserver for taxonomic classification of metagenomic reads
Gail L. Rosen; Erin R. Reichenberger; Aaron M. Rosenfeld
Motivation: Datasets from high-throughput sequencing technologies have yielded a vast amount of data about organisms in environmental samples. Yet, it is still a challenge to assess the exact organism content in these samples because the task of taxonomic classification is too computationally complex to annotate all reads in a dataset. An easy-to-use webserver is needed to process these reads. While many methods exist, only a few are publicly available on webservers, and out of those, most do not annotate all reads.
Results: We introduce a webserver that implements the naïve Bayes classifier (NBC) to classify all metagenomic reads to their best taxonomic match. Results indicate that NBC can assign next-generation sequencing reads to their taxonomic classification and can find significant populations of genera that other classifiers may miss.
Availability: Publicly available at: http://nbc.ece.drexel.edu.
Contact: gailr@ece.drexel.edu
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61
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