General Information
| Description | Learn de novo promoter architectures from genome-wide transcription start sites |
| Homepage | https://github.com/computationalBiology/NPLB/ |
Publications
No Promoter Left Behind (NPLB): learn de novo promoter architectures from genome-wide transcription start sites
Summary:
Promoters have diverse regulatory architectures and thus activate genes differently. For example, some have a TATA-box, many others do not. Even the ones with it can differ in its position relative to the transcription start site (TSS). No Promoter Left Behind (NPLB) is an efficient, organism-independent method for characterizing such diverse architectures directly from experimentally identified genome-wide TSSs, without relying on known promoter elements. As a test case, we show its application in identifying novel architectures in the fly genome.
Availability and implementation:
Web-server at http://nplb.ncl.res.in. Standalone also at https://github.com/computationalBiology/NPLB/ (Mac OSX/Linux).
Contact:
l.narlikar@ncl.res.in
Supplementary information:
Supplementary data are available at Bioinformatics online.
Related Tools
TSSer
Published December 2013
An automated method to identify transcription start sites in prokaryotic genomes from differential RNA sequencing data
CAGExploreR
Published March 2014
An R package for the analysis and visualization of promoter dynamics across multiple experiments
bTSSfinder
Published September 2016
A novel tool for the prediction of promoters in cyanobacteria and Escherichia coli
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
