General Information
| Description | An R/bioconductor package for biomarker discovery with protein microarrays |
| Homepage | http://www.bioconductor.org/packages/PAA/ |
Publications
PAA: an R/bioconductor package for biomarker discovery with protein microarrays
Summary:
The R/Bioconductor package Protein Array Analyzer ( PAA ) facilitates a flexible analysis of protein microarrays for biomarker discovery (esp., ProtoArrays). It provides a complete data analysis workflow including preprocessing and quality control, uni- and multivariate feature selection as well as several different plots and results tables to outline and evaluate the analysis results. As a main feature, PAA ’s multivariate feature selection methods are based on recursive feature elimination (e.g. SVM-recursive feature elimination, SVM-RFE) with stability ensuring strategies such as ensemble feature selection. This enables PAA to detect stable and reliable biomarker candidate panels.
Availability and implementation:
PAA is freely available (BSD 3-clause license) from http://www.bioconductor.org/packages/PAA/ .
Contact:
michael.turewicz@rub.de or martin.eisenacher@rub.de
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