General Information
| Description | Identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq) |
| Homepage | http://code.google.com/p/popoolation2/ |
Publications
PoPoolation2: identifying differentiation between populations using sequencing of pooled DNA samples (Pool-Seq)
Summary:
Sequencing pooled DNA samples (Pool-Seq) is the most cost-effective approach for the genome-wide comparison of population samples. Here, we introduce PoPoolation2, the first software tool specifically designed for the comparison of populations with Pool-Seq data. PoPoolation2 implements a range of commonly used measures of differentiation (FST, Fisher's exact test and Cochran-Mantel-Haenszel test) that can be applied on different scales (windows, genes, exons, SNPs). The result may be visualized with the widely used Integrated Genomics Viewer.
Availability and Implementation:
PoPoolation2 is implemented in Perl and R. It is freely available on http://code.google.com/p/popoolation2/
Contact:
christian.schloetterer@vetmeduni.ac.at
Supplementary Information:
Manual: http://code.google.com/p/popoolation2/wiki/Manual Test data and tutorial: http://code.google.com/p/popoolation2/wiki/Tutorial Validation: http://code.google.com/p/popoolation2/wiki/Validation
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