General Information
| Description | A tool for computing terabyte phylogenies |
| Homepage | https://github.com/stamatak/RAxML-Light-1.0.5 |
Publications
RAxML-Light: a tool for computing terabyte phylogenies
Motivation:
Due to advances in molecular sequencing and the increasingly rapid collection of molecular data, the field of phyloinformatics is transforming into a computational science. Therefore, new tools are required that can be deployed in supercomputing environments and that scale to hundreds or thousands of cores.
Results:
We describe RAxML-Light, a tool for large-scale phylogenetic inference on supercomputers under maximum likelihood. It implements a light-weight checkpointing mechanism, deploys 128-bit (SSE3) and 256-bit (AVX) vector intrinsics, offers two orthogonal memory saving techniques and provides a fine-grain production-level message passing interface parallelization of the likelihood function. To demonstrate scalability and robustness of the code, we inferred a phylogeny on a simulated DNA alignment (1481 taxa, 20 000 000 bp) using 672 cores. This dataset requires one terabyte of RAM to compute the likelihood score on a single tree.
Code Availability:
https://github.com/stamatak/RAxML-Light-1.0.5
Data Availability:
http://www.exelixis-lab.org/onLineMaterial.tar.bz2
Contact:
alexandros.stamatakis@h-its.org
Supplementary Information:
Supplementary data are available at Bioinformatics online.
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