General Information
| Description | Ribosome flow model application |
| Homepage | http://www.cs.tau.ac.il/~tamirtul/RFM_Installers/install.htm |
Publications
RFMapp: ribosome flow model application
Summary:
The RFMapp is a graphical user interface application based on the RFM (ribosome flow model), enabling the estimation of the translation elongation rates of messenger ribonucleic acids (mRNAs) and the profile of ribosomal densities along the mRNAs, in a computationally efficient way. The RFMapp is based on the approach previously described by Reuveni et al., and unlike other traditional approaches in the field, which are mainly related to the genes' mean codon translation efficiency, the RFM additionally considers the codon order, the ribosomes' size and their order. Thus, it has been shown that RFM outperforms traditional predictors when analyzing both heterologous and endogenous genes.
Availability and implementation:
Distributable cross-platform application and guideline are available for download at: http://www.cs.tau.ac.il/~tamirtul/RFM_Installers/install.htm
Contact:
tamirtul@post.tau.ac.il
Related Tools
RBSDesigner
Published August 2010
Software for designing synthetic ribosome binding sites that yields a desired level of protein expression
Codon Optimization OnLine (COOL)
Published April 2014
A web-based multi-objective optimization platform for synthetic gene design
Riborex
Published January 2017
Fast and flexible identification of differential translation from Ribo-seq data
RiboDiff
Published September 2016
Detecting changes of mRNA translation efficiency from ribosome footprints
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
