SBARS
Computational Tool
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General Information
DescriptionFast creation of dotplots for DNA sequences on different scales using GA-,GC-content
Homepagehttp://www.mpyatkov.github.com/sbars/
Publications
SBARS: fast creation of dotplots for DNA sequences on different scales using GA-,GC-content
Maxim I. Pyatkov; Anton N. Pankratov
Summary: Structural analysis of long DNA fragments, including chromosomes and whole genomes, is one of the main challenges in modern bioinformatics. Here, we propose an original approach based on spectral methods and its implementation called SBARS (Spectral-Based Approach for Repeats Search. The main idea of our approach is that repeated DNA structures are recognized not within the nucleotide sequence directly but within the function derived from this sequence. This allows us to investigate nucleotide sequences on different scales and decrease time complexity for dotplot creation down to .
Availability and implementation: Pre-compiled versions for Windows and Linux and documentation are available at http://mpyatkov.github.com/sbars/.
Contact: mpyatkov@gmail.com
Supplementary information: Supplementary data are available at Bioinformatics online.
DOI: https://doi.org/10.1093/bioinformatics/btu095
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