SpotXplore
Computational Tool
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General Information
DescriptionA Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks
Homepagehttp://www.win.tue.nl/∼mwestenb/spotxplore/
Publications
SpotXplore: a Cytoscape plugin for visual exploration of hotspot expression in gene regulatory networks
Michel A. Westenberg; Jos B.T.M. Roerdink; Oscar P. Kuipers; Sacha A.F.T. van Hijum
Summary: SpotXplore is a plugin for Cytoscape for extraction and visualization of differentially expressed subnetworks (hotspots) from gene networks. The hotspot-based visualization approach enables interactive exploration of regulatory interactions in differentially expressed gene sets, and it allows a researcher to explore gene expression in direct relation to the affected cellular gene network. The hotspots provide a view beyond the commonly used metabolic pathways and gene ontologies.
Availability: http://www.win.tue.nl/∼mwestenb/spotxplore/
Contact: m.a.westenberg@tue.nl
Supplementary information: Example data and user manual are available at SpotXplore's web site.
DOI: https://doi.org/10.1093/bioinformatics/btq535
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