General Information
| Description | Genome-wide TALEN off-target prediction |
| Homepage | http://www.jstacs.de/index.php/TALENoffer |
Publications
TALENoffer: genome-wide TALEN off-target prediction
Summary:
Transcription activator-like effector nucleases (TALENs) have become an accepted tool for targeted mutagenesis, but undesired off-targets remain an important issue. We present TALENoffer, a novel tool for the genome-wide prediction of TALEN off-targets. We show that TALENoffer successfully predicts known off-targets of engineered TALENs and yields a competitive runtime, scanning complete mammalian genomes within a few minutes.
Availability:
TALENoffer is available as a command line program from http://www.jstacs.de/index.php/TALENoffer and as a Galaxy server at http://galaxy.informatik.uni-halle.de.
Contact:
grau@informatik.uni-halle.de
Supplementary Information:
Supplementary data are available at Bioinformatics online.
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
