TALENoffer
Computational Tool
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General Information
DescriptionGenome-wide TALEN off-target prediction
Homepagehttp://www.jstacs.de/index.php/TALENoffer
Publications
TALENoffer: genome-wide TALEN off-target prediction
Jan Grau; Jens Boch; Stefan Posch
Summary: Transcription activator-like effector nucleases (TALENs) have become an accepted tool for targeted mutagenesis, but undesired off-targets remain an important issue. We present TALENoffer, a novel tool for the genome-wide prediction of TALEN off-targets. We show that TALENoffer successfully predicts known off-targets of engineered TALENs and yields a competitive runtime, scanning complete mammalian genomes within a few minutes.
Availability: TALENoffer is available as a command line program from http://www.jstacs.de/index.php/TALENoffer and as a Galaxy server at http://galaxy.informatik.uni-halle.de.
Contact: grau@informatik.uni-halle.de
Supplementary Information: Supplementary data are available at Bioinformatics online.
Metrics:
30
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