TRFolder-W
Computational Tool
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General Information
DescriptionA web server for telomerase RNA structure prediction in yeast genomes
Homepagehttp://rna-informatics.uga.edu/?f=software&p=TRFolder-w
Publications
TRFolder-W: a web server for telomerase RNA structure prediction in yeast genomes
Dong Zhang; Xingran Xue; Russell L. Malmberg; Liming Cai
Summary: TRFolder-W is a web server capable of predicting core structures of telomerase RNA (TR) in yeast genomes. TRFolder is a command-line Python toolkit for TR-specific structure prediction. We developed a web-version built on the django web framework, leveraging the work done previously, to include enhancements to increase flexibility of usage. To date, there are five core sub-structures commonly found in TR of fungal species, which are the template region, downstream pseudoknot, boundary element, core-closing stem and triple helix. The aim of TRFolder-W is to use the five core structures as fundamental units to predict potential TR genes for yeast, and to provide a user-friendly interface. Moreover, the application of TRFolder-W can be extended to predict the characteristic structure on species other than fungal species.
Availability: The web server TRFolder-W is available at http://rna-informatics.uga.edu/?f=software&p=TRFolder-w.
Contact : cai@cs.uga.edu
Supplementary information: http://rna-informatics.uga.edu/?f=software&p=TRFolder-w-supplement.
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