General Information
| Description | A tool for determining the threshold in short RNA-seq datasets |
| Homepage | http://cm.jefferson.edu/threshold-seq/ |
Publications
Threshold-seq: a tool for determining the threshold in short RNA-seq datasets
Summary:
We present ‘Threshold-seq,’ a new approach for determining thresholds in deep-sequencing datasets of short RNA transcripts. Threshold-seq addresses the critical question of how many reads need to support a short RNA molecule in a given dataset before it can be considered different from ‘background.’ The proposed scheme is easy to implement and incorporate into existing pipelines.
Availability and Implementation:
Source code of Threshold-seq is freely available as an R package at: http://cm.jefferson.edu/threshold-seq/
Contact:
isidore.rigoutsos@jefferson.edu
Supplementary information:
Supplementary data are available at Bioinformatics online.
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