General Information
| Description | An R package to visualize and score protein structure models based on sites of protein cross-linking |
| Homepage | http://brucelab.gs.washington.edu/software.php |
Publications
XLmap: an R package to visualize and score protein structure models based on sites of protein cross-linking
Motivation:
Chemical cross-linking with mass spectrometry (XL-MS) provides structural information for proteins and protein complexes in the form of crosslinked residue proximity and distance constraints between reactive residues. Utilizing spatial information derived from cross-linked residues can therefore assist with structural modeling of proteins. Selection of computationally derived model structures of proteins remains a major challenge in structural biology. The comparison of site interactions resulting from XL-MS with protein structure contact maps can assist the selection of structural models.
Availability and implementation:
XLmap was implemented in R and is freely available at: http://brucelab.gs.washington.edu/software.php.
Contact:
jimbruce@uw.edu
Supplementary information:
Supplementary data are available at Bioinformatics online.
Related Tools
SQID-XLink
Published July 2012
Implementation of an intensity-incorporated algorithm for cross-linked peptide identification
XLinkDB 2.0
Published April 2016
Integrated, large-scale structural analysis of protein crosslinking data
FAIR Evaluation
Sorry, you must be signed in to evaluate this object.
