caRpools
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General Information
DescriptionAn R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens
Homepagehttp://github.com/boutroslab/caRpools
Publications
caRpools: an R package for exploratory data analysis and documentation of pooled CRISPR/Cas9 screens
Jan Winter; Marco Breinig; Florian Heigwer; Dirk Brügemann; Svenja Leible; Oliver Pelz; Tianzuo Zhan; Michael Boutros
Motivation: Genetic screens by CRISPR/Cas9-mediated genome engineering have become a powerful tool for functional genomics. However, there is currently a lack of end-to-end software pipelines to analyze CRISPR/Cas9 screens based on next generation sequencing.
Results: The CRISPR-AnalyzeR for pooled screens (caRpools) is an R package for exploratory data analysis that provides a complete workflow to analyze CRISPR/Cas9 screens. To further support the analysis of large-scale screens, caRpools integrates screening documentation and generation of standardized analysis reports.
Availability and implementation: caRpools, manuals and an open virtual appliance are available at http://github.com/boutroslab/caRpools .
Contact: m.boutros@dkfz.de
Metrics:
2
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