General Information
| Description | Demography-aware inference of identity-by-descent tracts in unrelated individuals |
| Homepage | http://sourceforge.net/projects/dical-ibd |
Publications
diCal-IBD: demography-aware inference of identity-by-descent tracts in unrelated individuals
Summary:
We present a tool, diCal-IBD, for detecting identity-by-descent (IBD) tracts between pairs of genomic sequences. Our method builds on a recent demographic inference method based on the coalescent with recombination, and is able to incorporate demographic information as a prior. Simulation study shows that diCal-IBD has significantly higher recall and precision than that of existing single-nucleotide polymorphism–based IBD detection methods, while retaining reasonable accuracy for IBD tracts as small as 0.1 cM.
Availability:
http://sourceforge.net/projects/dical-ibd
Contact:
yss@eecs.berkeley.edu
Supplementary information:
Supplementary data are available at Bioinformatics online.
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