General Information
| Description | A comprehensive data and phylogenomics resource for prokaryotic transcription factors |
| Homepage | http://centre.bioinformatics.zj.cn/proTF |
Publications
proTF: a comprehensive data and phylogenomics resource for prokaryotic transcription factors
Summary:
Investigation of transcription factors (TFs) is of extreme significance for gleaning more information about the mechanisms underlying the dynamic transcriptional regulatory network. Herein, proTF is constructed to serve as a comprehensive data resource and phylogenomics analysis platform for prokaryotic TFs. It has many prominent characteristics: (i) detailed annotation information, including basic sequence features, domain organization, sequence homolog and sequence composition, was extensively collected, and then visually displayed for each TF entry in all prokaryotic genomes; (ii) workset was employed as the basic frame to provide an efficient way to organize the retrieved data and save intermediate records; and (iii) a number of elaborated tools for phylogenomics analysis were implemented to investigate the evolutionary roles of specific TFs. In conclusion, proTF dedicates to the prokaryotic TFs with integrated multi-function, which will become a valuable resource for prokaryotic transcriptional regulatory network in the post-genomic era.
Availability:
http://centre.bioinformatics.zj.cn/proTF
Contact:
med_bp@zju.edu.cn; iamwujy@yahoo.com.cn
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