IKK-2-INHIBITOR-V (BRD-K74305673)
Overview
- pert_id
- BRD-K74305673
- Name
- IKK-2-inhibitor-V
- Collection
- BIOA
- MOA
- IKK inhibitor, NFkB pathway inhibitor
- Target(s)
- IKBKB
- Indication(s)
- Unknown
- Phase
- Phase 1
- Canonical SMILES
- Oc1ccc(Cl)cc1C(=O)Nc2cc(cc(c2)C(F)(F)F)C(F)(F)F
- InChI key
- InChIKey=CHILCFMQWMQVAL-UHFFFAOYSA-N
- InChI string
- InChI=1S/C15H8ClF6NO2/c16-9-1-2-12(24)11(6-9)13(25)23-10-4-7(14(17,18)19)3-8(5-10)15(20,21)22/h1-6,24H,(H,23,25)
- Molecular formula
- C15H8ClF6NO2
- Molecular weight
- 383.673
External links
- PubChem
- 5081913
- Wikipedia
- http://www.emdmillipore.com/life-science-research/ikk-2-inhibitor-v/EMD_BIO-401482/p_6Cub.s1LUxkAAAEWxWEfVhTm?PortalCatalogID=merck4biosciences&CountryName=United+States+of+America
- SEP-L1000
- BRD-K74305673
Predicted MOAs
| MOA | Probability |
|---|---|
| EGFR inhibitor | 0.1871 |
| cyclooxygenase inhibitor | 0.1481 |
| MEK inhibitor | 0.1094 |
| RAF inhibitor | 0.0969 |
| topoisomerase inhibitor | 0.0381 |
| CDK inhibitor | 0.0380 |
| HDAC inhibitor | 0.0360 |
| retinoid receptor agonist | 0.0344 |
| PARP inhibitor | 0.0310 |
| PLK inhibitor | 0.0299 |
Chemical structure
