VANOXERINE (BRD-K32501161)
Overview
- pert_id
- BRD-K32501161
- Name
- vanoxerine
- Synonyms
- GBR-12909
- Collection
- BIOA
- MOA
- dopamine uptake inhibitor
- Target(s)
- SLC6A3
- Indication(s)
- Unknown
- Phase
- Phase 3
- Canonical SMILES
- Fc1ccc(cc1)C(OCCN2CCN(CCCc3ccccc3)CC2)c4ccc(F)cc4
- InChI key
- InChIKey=NAUWTFJOPJWYOT-UHFFFAOYSA-N
- InChI string
- InChI=1S/C28H32F2N2O/c29-26-12-8-24(9-13-26)28(25-10-14-27(30)15-11-25)33-22-21-32-19-17-31(18-20-32)16-4-7-23-5-2-1-3-6-23/h1-3,5-6,8-15,28H,4,7,16-22H2
- Molecular formula
- C28H32F2N2O
- Molecular weight
- 450.563
External links
- PubChem
- 10238982
- Wikipedia
- http://en.wikipedia.org/wiki/Vanoxerine
- SEP-L1000
- BRD-K32501161
Predicted MOAs
| MOA | Probability |
|---|---|
| calcium channel blocker | 0.8341 |
| dopamine receptor antagonist | 0.0751 |
| histamine receptor antagonist | 0.0541 |
| adrenergic receptor antagonist | 0.0111 |
| cyclooxygenase inhibitor | 0.0027 |
| PI3K inhibitor | 0.0021 |
| mTOR inhibitor | 0.0019 |
| PLK inhibitor | 0.0017 |
| CDK inhibitor | 0.0016 |
| HDAC inhibitor | 0.0016 |
Chemical structure
