AG-14361 (BRD-K00615600)
Overview
- pert_id
- BRD-K00615600
- Name
- AG-14361
- Synonyms
- S2178
- Collection
- STRD
- Summary
- AG14361 is a potent inhibitor of PARP1 with Ki of < 5 nM. - See more at: http://www.selleckchem.com/products/AG14361.html#sthash.wMyRqJfy.dpuf
- MOA
- PARP inhibitor
- Target(s)
- PARP1
- Indication(s)
- Unknown
- Phase
- Preclinical
- Canonical SMILES
- CN(C)Cc1ccc(cc1)c2nc3cccc4C(=O)NCCn2c43
- InChI key
- InChIKey=SEKJSSBJKFLZIT-UHFFFAOYSA-N
- InChI string
- InChI=1S/C19H20N4O/c1-22(2)12-13-6-8-14(9-7-13)18-21-16-5-3-4-15-17(16)23(18)11-10-20-19(15)24/h3-9H,10-12H2,1-2H3,(H,20,24)
- Molecular formula
- C19H20N4O
- Molecular weight
- 320.388
External links
- PubChem
- 9840076
- Wikipedia
- http://www.abmole.com/product.asp?id=1645
- SEP-L1000
- BRD-K00615600
Predicted MOAs
| MOA | Probability |
|---|---|
| PARP inhibitor | 0.8542 |
| CDK inhibitor | 0.0299 |
| histamine receptor antagonist | 0.0152 |
| adrenergic receptor antagonist | 0.0123 |
| dopamine receptor antagonist | 0.0119 |
| calcium channel blocker | 0.0092 |
| cyclooxygenase inhibitor | 0.0087 |
| Aurora kinase inhibitor | 0.0060 |
| PI3K inhibitor | 0.0053 |
| MEK inhibitor | 0.0047 |
Chemical structure
