AS-605240 (BRD-K41895714)
Overview
- pert_id
- BRD-K41895714
- Name
- AS-605240
- Synonyms
- S1410
- Collection
- BIOA
- Summary
- AS-605240 is a novel, potent and selective PI3Kγ inhibitor with IC50 of 8 nM.
- MOA
- Unknown
- Target(s)
- Unknown
- Indication(s)
- Unknown
- Phase
- Unknown
- Canonical SMILES
- O=C1NC(=O)C(S1)=C/c1ccc2nccnc2c1
- InChI key
- InChIKey=SQWZFLMPDUSYGV-UXBLZVDNSA-N
- InChI string
- InChI=1S/C12H7N3O2S/c16-11-10(18-12(17)15-11)6-7-1-2-8-9(5-7)14-4-3-13-8/h1-6H,(H,15,16,17)/b10-6+
- Molecular formula
- C12H7N3O2S
- Molecular weight
- 257.268
External links
- PubChem
- 10377751
- Wikipedia
- http://www.selleckchem.com/products/AS-605240.html
- SEP-L1000
- BRD-K41895714
Predicted MOAs
| MOA | Probability |
|---|---|
| PI3K inhibitor | 0.8832 |
| PARP inhibitor | 0.0329 |
| cyclooxygenase inhibitor | 0.0110 |
| CDK inhibitor | 0.0109 |
| calcium channel blocker | 0.0064 |
| dopamine receptor antagonist | 0.0059 |
| HSP inhibitor | 0.0054 |
| PLK inhibitor | 0.0049 |
| HDAC inhibitor | 0.0045 |
| topoisomerase inhibitor | 0.0034 |
Chemical structure
