TAK-715 (BRD-K52751261)
Overview
- pert_id
- BRD-K52751261
- Name
- TAK-715
- Synonyms
- S2928
- Collection
- BIOA
- Summary
- TAK 715 is a p38 MAPK inhibitor for p38α with IC50 of 7.1 nM.
- MOA
- p38 MAPK inhibitor
- Target(s)
- MAPK14
- Indication(s)
- Unknown
- Phase
- Phase 2
- Canonical SMILES
- CCc1nc(c(s1)-c1ccnc(NC(=O)c2ccccc2)c1)-c1cccc(C)c1
- InChI key
- InChIKey=HEKAIDKUDLCBRU-UHFFFAOYSA-N
- InChI string
- InChI=1S/C24H21N3OS/c1-3-21-27-22(18-11-7-8-16(2)14-18)23(29-21)19-12-13-25-20(15-19)26-24(28)17-9-5-4-6-10-17/h4-15H,3H2,1-2H3,(H,25,26,28)
- Molecular formula
- C24H21N3OS
- Molecular weight
- 399.508
External links
- PubChem
- 9952773
- Wikipedia
- http://www.selleckchem.com/products/tak-715.html
- SEP-L1000
- BRD-K52751261
Predicted MOAs
| MOA | Probability |
|---|---|
| cyclooxygenase inhibitor | 0.3741 |
| PI3K inhibitor | 0.1936 |
| PARP inhibitor | 0.1252 |
| dopamine receptor antagonist | 0.0445 |
| PLK inhibitor | 0.0395 |
| histamine receptor antagonist | 0.0356 |
| EGFR inhibitor | 0.0237 |
| HDAC inhibitor | 0.0184 |
| MEK inhibitor | 0.0180 |
| Aurora kinase inhibitor | 0.0173 |
Chemical structure
