AG-879 (BRD-K59469039)
Overview
- pert_id
- BRD-K59469039
- Name
- AG-879
- Synonyms
- AG-879
- Collection
- BIOA
- MOA
- tyrosine kinase inhibitor
- Target(s)
- ERBB2, KDR, NTRK1
- Indication(s)
- Unknown
- Phase
- Preclinical
- Canonical SMILES
- CC(C)(C)c1cc(/C=C(C#N)/C(=S)N)cc(c1O)C(C)(C)C
- InChI key
- InChIKey=XRZYELWZLNAXGE-KPKJPENVSA-N
- InChI string
- InChI=1S/C18H24N2OS/c1-17(2,3)13-8-11(7-12(10-19)16(20)22)9-14(15(13)21)18(4,5)6/h7-9,21H,1-6H3,(H2,20,22)/b12-7+
- Molecular formula
- C18H24N2OS
- Molecular weight
- 316.461
External links
- PubChem
- 5353385
- SEP-L1000
- BRD-K59469039
Predicted MOAs
| MOA | Probability |
|---|---|
| retinoid receptor agonist | 0.2202 |
| MEK inhibitor | 0.1999 |
| HSP inhibitor | 0.0775 |
| NFkB pathway inhibitor | 0.0706 |
| tubulin polymerization inhibitor | 0.0610 |
| EGFR inhibitor | 0.0438 |
| histamine receptor antagonist | 0.0348 |
| RAF inhibitor | 0.0345 |
| cyclooxygenase inhibitor | 0.0307 |
| estrogen receptor agonist | 0.0306 |
Chemical structure
