FLECAINIDE (BRD-A09472452)
Overview
- pert_id
- BRD-A09472452
- Name
- flecainide
- Collection
- BIOA
- MOA
- sodium channel blocker
- Target(s)
- KCNA5, KCNA7, SCN4A, SCN5A
- Indication(s)
- ventricular tachycardia (VT), atrial fibrillation (AF), ventricular arrhythmias
- Phase
- Launched
- Canonical SMILES
- FC(F)(F)COc1ccc(OCC(F)(F)F)c(c1)C(=O)NCC2CCCCN2
- InChI key
- InChIKey=DJBNUMBKLMJRSA-UHFFFAOYSA-N
- InChI string
- InChI=1S/C17H20F6N2O3/c18-16(19,20)9-27-12-4-5-14(28-10-17(21,22)23)13(7-12)15(26)25-8-11-3-1-2-6-24-11/h4-5,7,11,24H,1-3,6,8-10H2,(H,25,26)
- Molecular formula
- C17H20F6N2O3
- Molecular weight
- 414.343
External links
- PubChem
- 3356
- Wikipedia
- http://en.wikipedia.org/wiki/Flecainide
- SEP-L1000
- BRD-A09472452
Predicted MOAs
| MOA | Probability |
|---|---|
| adrenergic receptor antagonist | 0.5472 |
| topoisomerase inhibitor | 0.0758 |
| calcium channel blocker | 0.0427 |
| histamine receptor antagonist | 0.0260 |
| HDAC inhibitor | 0.0254 |
| dopamine receptor antagonist | 0.0232 |
| tubulin polymerization inhibitor | 0.0221 |
| PLK inhibitor | 0.0219 |
| MEK inhibitor | 0.0202 |
| mTOR inhibitor | 0.0199 |
Chemical structure
Diagnoses (based on Mount Sinai EHR)
Top diagnoses associated with flecainide:
Co-prescribed Drugs (based on Mount Sinai EHR)
Top coprescribed drugs of flecainide:
Age Distribution (based on Mount Sinai EHR)
Probability distribution for the prescription of flecainide across different ages: