!direction	-1
!num_genes	236
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Thymus (of ovariectomized C57BL/6) - 6 Days
!organism	mouse
!end_metadata
DYNLL1	-0.069072
LBR	-0.063244
SLC38A2	-0.061812
HSPD1	-0.055060
DNAJA1	-0.054085
AP3S1	-0.053604
POLR2K	-0.049351
ETS2	-0.049060
CDCA7	-0.046238
TCF12	-0.045506
CCT6A	-0.044959
DEK	-0.044197
HNRNPF	-0.043893
CDK2AP1	-0.041296
RPS25	-0.041143
HSP90AA1	-0.041009
JUND	-0.040991
C11orf31	-0.040317
CD8A	-0.040240
COX4I1	-0.037949
KIAA0101	-0.037574
EZH2	-0.037453
RPL22	-0.036928
VBP1	-0.036131
TRIM59	-0.035595
HSPH1	-0.035272
CHORDC1	-0.035102
SPCS2	-0.034547
HMGCS1	-0.034423
PANK3	-0.034198
SUMO2	-0.034035
ATL2	-0.032193
SWI5	-0.032028
TFDP1	-0.031910
UQCRHL	-0.031905
CPNE1	-0.031679
HMGB2	-0.031379
RRM2	-0.030626
EEF1E1	-0.029913
RAC2	-0.029422
CCNG2	-0.029399
CNOT6	-0.029364
CSNK2B	-0.029154
PSMA2	-0.029102
RPL27A	-0.029067
DNAJB1	-0.029066
RAG1	-0.028907
BCL11B	-0.028180
ELAVL1	-0.027638
TAF9	-0.027584
MMADHC	-0.027476
RAP1B	-0.026952
HAT1	-0.026936
ARID1A	-0.026670
POLR2I	-0.026636
SEP15	-0.026596
PITPNA	-0.026544
USMG5	-0.026424
ADCY6	-0.026384
KPNA2	-0.026277
NDUFC2	-0.026196
MRPL24	-0.026055
EIF3D	-0.026037
CNOT1	-0.025914
SRRT	-0.025741
PPP1CA	-0.025713
CACYBP	-0.025687
FAM49B	-0.025619
TUBA1A	-0.025471
NUDT21	-0.025274
HSP90AB1	-0.025212
PFDN6	-0.024916
SEPT7	-0.024893
MRFAP1	-0.024704
TRAT1	-0.024703
DCK	-0.024170
HDAC7	-0.024165
RNF44	-0.023977
SNRNP27	-0.023867
PSMB7	-0.023683
RAG2	-0.023394
MRPL18	-0.023356
TNKS2	-0.023343
RPL12	-0.023341
SNRPD1	-0.023196
PSMC4	-0.023154
IDI1	-0.023060
DOCK2	-0.022828
RFWD2	-0.022645
NHP2L1	-0.022637
CLIC1	-0.022607
COPA	-0.022584
GAPDH	-0.022561
PSMC3	-0.022486
UBE2E1	-0.022462
TIPIN	-0.022312
COPS3	-0.022281
DUT	-0.022240
NEDD8	-0.022160
RRM1	-0.022108
SFT2D1	-0.021979
CAPZA1	-0.021709
RPS19	-0.021696
DBI	-0.021453
ITK	-0.021410
IMMP1L	-0.021257
DYNLRB1	-0.021122
SQLE	-0.021101
MYL12B	-0.021096
PSMC2	-0.020776
AP1B1	-0.020738
IVNS1ABP	-0.020584
HELLS	-0.020584
OSER1	-0.020551
PABPC1	-0.020500
PRMT1	-0.020480
PSMA7	-0.020425
SYVN1	-0.020371
PPP4C	-0.020309
FKBP3	-0.020269
RBBP7	-0.020092
DDX19A	-0.019984
TOPBP1	-0.019949
SRSF2	-0.019831
HDAC2	-0.019820
CCT8	-0.019789
E2F8	-0.019772
HNRNPH2	-0.019752
ATAD2B	-0.019594
SOD1	-0.019540
RBM38	-0.019505
G3BP1	-0.019468
SPO11	-0.019451
RNF145	-0.019372
SMC4	-0.019337
WDR78	-0.019212
FH	-0.019155
PDCD10	-0.019150
LAMTOR5	-0.019140
TOMM20	-0.019139
ASF1B	-0.019129
EDF1	-0.019059
GIMAP6	-0.019024
CYCS	-0.018995
STK38	-0.018947
ACTR3	-0.018926
FBXL12	-0.018771
TMX1	-0.018652
SELK	-0.018644
EIF1B	-0.018593
MRPL30	-0.018592
OSTC	-0.018464
CETN3	-0.018419
FKBP1A	-0.018397
DNAJC15	-0.018393
STAG2	-0.018380
HINT1	-0.018293
TMEM261	-0.018275
NOP10	-0.018246
YWHAH	-0.018225
SRSF1	-0.018187
NUP107	-0.018175
MSH6	-0.018133
UBALD1	-0.018082
CSTF3	-0.018032
HNRNPM	-0.018020
NUDT5	-0.017926
SHFM1	-0.017917
MAD2L1	-0.017898
MRTO4	-0.017856
CPSF7	-0.017816
MAT2B	-0.017801
GTF2H4	-0.017592
PPP1R8	-0.017562
ST13	-0.017480
MATR3	-0.017431
DARS	-0.017396
HNRNPH1	-0.017384
FAM76B	-0.017372
CDK2	-0.017154
MOB4	-0.017131
SLA	-0.017067
S100A10	-0.017003
PRC1	-0.016983
HIAT1	-0.016973
CCND3	-0.016952
GNB2	-0.016921
STIP1	-0.016745
CHCHD1	-0.016722
CHIC2	-0.016691
SRSF7	-0.016646
CDC6	-0.016624
IKZF1	-0.016614
FAM120A	-0.016545
DGKZ	-0.016478
FDPS	-0.016461
RHOH	-0.016459
HMGN1	-0.016443
AKIRIN1	-0.016438
MNS1	-0.016434
SRP14	-0.016286
SMARCD2	-0.016212
AHSA1	-0.016165
BANF1	-0.016113
DNAJB9	-0.016090
ATP6V1G1	-0.015976
ITGAL	-0.015896
PDS5A	-0.015862
MED10	-0.015803
API5	-0.015800
GMNN	-0.015797
MGEA5	-0.015792
U2AF2	-0.015679
ANXA5	-0.015647
RPS27A	-0.015544
MRPL32	-0.015524
SUB1	-0.015509
RGCC	-0.015498
EIF4G3	-0.015485
PSENEN	-0.015483
LSM5	-0.015453
SMC2	-0.015444
TOP1	-0.015440
NABP1	-0.015312
PPP1CB	-0.015304
MAST3	-0.015304
C5orf24	-0.015268
ABLIM1	-0.015264
MAZ	-0.015239
KCNA3	-0.015221
MOB1A	-0.015159
NXF1	-0.015111
NUSAP1	-0.015104
TFAM	-0.015089
ZBTB18	-0.015006
CDC42SE2	-0.014962