!direction	-1
!num_genes	233
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	mouse
!drug_name	Estradiol
!smiles	CC12CCC3C(C1CCC2O)CCC4=C3C=CC(=C4)O
!drugbank_id	DB00783
!pubchem_cid	5757
!cell_type	Uterus - single injection of 400 ug/kg - 24 Hours after treatment
!organism	mouse
!end_metadata
LTBP4	-0.136295
DCN	-0.122024
SPARCL1	-0.120670
TPT1	-0.112455
RPL13	-0.104174
LSP1	-0.095661
APP	-0.087651
RPS3	-0.084036
LAPTM4A	-0.084030
IGFBP3	-0.083276
PLAT	-0.082731
EEF2	-0.081968
APCDD1	-0.079735
EEF1A1	-0.077127
RPS23	-0.076860
ID2	-0.075798
EIF4A2	-0.074082
ISLR	-0.072870
PLAC8	-0.072058
SOX17	-0.069861
RPS19	-0.069801
GSN	-0.069030
KCTD12	-0.068403
RPLP0	-0.068209
ITM2B	-0.067104
RPS5	-0.065999
HK1	-0.065489
GNB2L1	-0.065472
CTSD	-0.064019
SERPING1	-0.063843
RHOB	-0.062684
RPL5	-0.061016
RPL19	-0.060498
CPE	-0.059735
TGFBI	-0.059123
GSTM5	-0.057141
WDR92	-0.056195
ITM2C	-0.055301
RPL10A	-0.054748
PLTP	-0.054553
MYH11	-0.054254
RPL7	-0.053075
RPL10	-0.052840
FMO1	-0.052513
SFRP2	-0.052063
GAS1	-0.051976
RPS15A	-0.051916
MYLK	-0.051299
UBC	-0.050359
B2M	-0.048548
NREP	-0.047757
RPL21	-0.047085
RPL3	-0.046450
RPS24	-0.045813
POSTN	-0.045600
APOE	-0.045535
ACAA2	-0.045506
RPS12	-0.044894
RPL28	-0.043524
RPS7	-0.043279
YPEL3	-0.043229
PENK	-0.042920
RPS27A	-0.042614
RABAC1	-0.042545
ACTA2	-0.042526
NPNT	-0.042380
MSX1	-0.042071
SERINC3	-0.042039
TGFB1I1	-0.041236
RPS28	-0.040919
COL3A1	-0.040867
ZBTB20	-0.040150
WFDC2	-0.040143
MGP	-0.039769
CST3	-0.039307
TIMP3	-0.038944
MDK	-0.038483
SVIL	-0.038341
MORF4L1	-0.037773
TXNIP	-0.037457
WLS	-0.036685
RIN2	-0.036300
RPS10	-0.035030
H19	-0.034768
BGN	-0.033964
ZFP36L1	-0.033962
RPS26	-0.033447
SESN1	-0.033318
RPS2	-0.032905
CLK1	-0.032817
TCF4	-0.032660
GTF2I	-0.032466
RPL8	-0.031801
CALB1	-0.031663
PGRMC1	-0.031503
FXYD1	-0.031485
TMEM123	-0.031264
FAM8A1	-0.030549
RECK	-0.030468
RARRES2	-0.030414
LBP	-0.030012
NFIX	-0.029827
RNF167	-0.029795
ACTG1	-0.029620
HDC	-0.029433
MAP1LC3B	-0.029171
TNXB	-0.029161
CSRP1	-0.029034
ID4	-0.028973
GABARAPL1	-0.028731
CTDSP2	-0.028526
MCAM	-0.028501
REV3L	-0.028414
RPL6	-0.028311
EID1	-0.028296
ENPP2	-0.028199
CNN3	-0.028108
CLIC4	-0.027979
MARCKSL1	-0.027955
IGFBP6	-0.027686
AHNAK	-0.027623
IGF1R	-0.027468
BPIFB1	-0.027409
RGS2	-0.026971
NDP	-0.026935
PRNP	-0.026907
SMAD1	-0.026869
MAF1	-0.026653
RPS11	-0.026240
DDX5	-0.026142
MEF2D	-0.026096
DPT	-0.025964
RERE	-0.025745
RMND5A	-0.025489
RAMP1	-0.025342
NSA2	-0.025043
AQP1	-0.025038
MYL12A	-0.024893
GPC3	-0.024859
FTH1	-0.024767
MXD4	-0.024522
SUN2	-0.024458
SPOCK2	-0.024391
CD74	-0.024044
SCARB1	-0.023581
ALDH2	-0.023577
APLP2	-0.023554
SH3BGRL	-0.023354
HOXA11	-0.023289
BRI3	-0.023070
SPTBN1	-0.023042
DOCK9	-0.022977
TAGLN	-0.022683
PDXK	-0.022587
FBLN1	-0.022289
PTOV1	-0.022211
CDH5	-0.022208
PTGER4	-0.022182
SPPL3	-0.021994
PTCH1	-0.021981
SQSTM1	-0.021980
TSC22D1	-0.021913
NUMA1	-0.021830
DDX17	-0.021715
TCN2	-0.021712
PTTG1IP	-0.021549
MBTPS1	-0.021546
PRKAR1A	-0.021456
CD93	-0.021439
C5orf15	-0.021233
ID3	-0.021218
PCBP2	-0.021052
ZBTB16	-0.021008
SMTN	-0.020992
ERGIC3	-0.020934
C12orf57	-0.020741
GNAS	-0.020409
IMPDH2	-0.020376
PNRC2	-0.020161
ATP2A3	-0.020009
ECH1	-0.019952
HDAC5	-0.019950
AES	-0.019924
ACTB	-0.019650
SPARC	-0.019551
PPAP2B	-0.019502
GDI1	-0.019433
OAZ2	-0.019382
PAPSS1	-0.019240
CACHD1	-0.019187
GLTSCR2	-0.019085
CTSF	-0.018991
FZD2	-0.018899
SLC25A36	-0.018747
LRRC58	-0.018603
ITGB1	-0.018532
PKD2	-0.018488
CPXM2	-0.018479
RPL27A	-0.018471
KMT2E	-0.018410
HADH	-0.018391
GDF10	-0.018380
TMED4	-0.018307
RPS4Y1	-0.018299
SGCE	-0.018297
SMAD4	-0.018249
MPRIP	-0.018247
MMP14	-0.018131
SLMAP	-0.018121
ANGPTL2	-0.018077
FOXO3	-0.018034
DSTN	-0.017994
CD9	-0.017976
NDRG1	-0.017923
KLF9	-0.017853
CLDN5	-0.017829
TMEM131	-0.017813
GRINA	-0.017721
PSMC6	-0.017584
RSU1	-0.017567
PLS3	-0.017542
FRYL	-0.017432
BNIP3L	-0.017397
WDR6	-0.017346
CBX6	-0.017331
ST5	-0.017245
COL1A2	-0.017123
INMT	-0.017120
TRIO	-0.017016
THY1	-0.016980
IFITM3	-0.016947
DKK3	-0.016821
DENND5A	-0.016735