!direction	-1
!num_genes	220
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Vincristine
!smiles	CCC1(CC2CC(C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)C78CCN9C7C(C=CC9)(C(C(C8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O
!drugbank_id	DB00541
!pubchem_cid	5978
!cell_type	SKOV3
!organism	human
!end_metadata
ALDH1A1	-0.147474
AKR1B1	-0.134952
ID1	-0.131138
S100A2	-0.110149
DDIT4	-0.103265
SNHG1	-0.098860
ND2	-0.097323
AKR1C3	-0.091774
PSAT1	-0.086013
TNFRSF12A	-0.082749
COX2	-0.075092
GTF3C6	-0.072521
RAN	-0.070790
GADD45A	-0.065654
DHRS2	-0.065019
HMGN3	-0.063464
FTL	-0.061064
IARS	-0.060963
XPOT	-0.060223
ZCRB1	-0.055105
PRSS3	-0.052915
ASNS	-0.051966
NDUFAB1	-0.050834
TMBIM4	-0.049891
GARS	-0.049545
HSPA9	-0.048025
EIF1	-0.047366
HSP90AB1	-0.047332
ATF4	-0.046543
HN1	-0.045836
EIF2S2	-0.045757
PFN1	-0.045212
CKS1B	-0.044033
NPM1	-0.043473
HSP90AA1	-0.043062
GGCT	-0.041512
PSMB3	-0.041108
S100A10	-0.040863
PGAM1	-0.040109
PRDX1	-0.039815
ZFAS1	-0.039506
ODC1	-0.039403
DDX21	-0.038639
SLC38A2	-0.038272
MAPK6	-0.037799
TRIB3	-0.037774
KANSL2	-0.037588
PSMA1	-0.037425
DYNLT1	-0.036900
ID3	-0.035587
TMBIM6	-0.035500
ATP5F1	-0.035049
EIF4A1	-0.035022
YWHAG	-0.034764
HSPD1	-0.034750
TUBA1C	-0.034682
AP3S1	-0.034639
NOP58	-0.034582
SLC7A11	-0.034470
NARS	-0.034382
H3F3B	-0.034296
RPL7L1	-0.034123
MRPL3	-0.033991
AARS	-0.033766
ATP5C1	-0.033563
RACGAP1	-0.033561
SSB	-0.033440
SLIRP	-0.033396
MRPS10	-0.033080
SPP1	-0.033005
RPL23A	-0.032288
NDUFV2	-0.031842
NUPR1	-0.031810
S100A4	-0.031773
EIF5	-0.031585
RPF2	-0.030982
PSG3	-0.030923
NME1	-0.030875
SEPHS2	-0.030275
NQO2	-0.030176
TSPAN1	-0.029875
CCT3	-0.029727
TRMT112	-0.029398
PPA1	-0.028839
SLC3A2	-0.028833
SERBP1	-0.028694
RRM2	-0.028528
GHITM	-0.028396
COX1	-0.028299
HMGB1	-0.028142
ANP32B	-0.028078
RBBP7	-0.027977
PSMD14	-0.027798
JTB	-0.027795
HINT1	-0.027662
KPNB1	-0.026917
COL5A2	-0.026292
MTHFD2	-0.026226
TXNDC12	-0.026209
PFDN2	-0.025541
DBI	-0.025266
OAT	-0.025189
GAS5	-0.025171
RPL4	-0.025014
NT5C3A	-0.024785
SLC25A5	-0.024646
RPS2	-0.024626
CYCS	-0.024526
NQO1	-0.024494
PSMC1	-0.024379
HDDC2	-0.024324
PTPLAD1	-0.024299
GTSF1	-0.024169
CCT2	-0.024150
SNRPG	-0.024076
ITGAE	-0.024039
RNPS1	-0.023855
EIF4H	-0.023846
PPIA	-0.023832
ECI2	-0.023787
C1QBP	-0.023465
HSPA5	-0.023377
PDIA6	-0.023095
SNHG8	-0.022923
MARS	-0.022907
DEK	-0.022867
C1orf43	-0.022772
DAW1	-0.022682
TRIM16	-0.022365
ETF1	-0.022209
DHX15	-0.022199
IMPA2	-0.022195
TRNP1	-0.022127
EIF3A	-0.022030
SHFM1	-0.021930
NCL	-0.021911
SMIM15	-0.021855
EIF5A	-0.021795
TMEM5	-0.021683
RNF145	-0.021640
CYSTM1	-0.021633
BUB3	-0.021494
TUBA1B	-0.021472
LIMA1	-0.021194
PIR	-0.021182
PPP1R15B	-0.021156
PRMT1	-0.021132
SNRNP25	-0.021032
PEG10	-0.020940
TXNDC17	-0.020632
HMGN2	-0.020464
USP1	-0.020425
BZW1	-0.020421
DKC1	-0.020279
XRCC6	-0.020250
ECHDC1	-0.020221
MIEN1	-0.020208
CD164	-0.019995
HMGB2	-0.019920
TXNL4A	-0.019837
SNX3	-0.019828
AATF	-0.019817
GLO1	-0.019816
IGFBP3	-0.019776
NDUFC1	-0.019741
C14orf2	-0.019687
PIGP	-0.019531
ENOPH1	-0.019438
COX3	-0.019319
KTN1	-0.019088
PLS3	-0.019018
PRDX3	-0.018825
FAM129A	-0.018802
LDHB	-0.018749
SMYD3	-0.018685
POLR2J	-0.018619
PAICS	-0.018606
PDZK1	-0.018569
KIAA0101	-0.018537
ARF6	-0.018515
PNPT1	-0.018513
ETFA	-0.018450
BOLA3	-0.018337
ATP5B	-0.018331
YME1L1	-0.018264
ANP32E	-0.018163
C6orf62	-0.018074
DDIT3	-0.017983
HNRNPA2B1	-0.017929
PITPNB	-0.017916
ANO6	-0.017884
CCT6A	-0.017824
PFKM	-0.017818
UQCRC2	-0.017772
SLC7A5	-0.017541
HAX1	-0.017521
EPRS	-0.017366
MTIF2	-0.017353
UGDH	-0.017289
PSG6	-0.017259
RPL10A	-0.017208
MRPS33	-0.017145
CBWD1	-0.017144
SLC1A5	-0.017087
COPRS	-0.017083
FAM35A	-0.017028
CBX1	-0.017012
PRPF8	-0.016992
PSMB6	-0.016976
DNAJA3	-0.016937
SMNDC1	-0.016889
HNRNPK	-0.016871
DNAJB11	-0.016862
YWHAE	-0.016861
MTX2	-0.016826
METTL5	-0.016813
BMI1	-0.016801
PPP4C	-0.016695
STAG2	-0.016685
SRP19	-0.016642