!direction	-1
!num_genes	440
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	foretinib
!smiles	COC1=CC2=C(C=CN=C2C=C1OCCCN3CCOCC3)OC4=C(C=C(C=C4)NC(=O)C5(CC5)C(=O)NC6=CC=C(C=C6)F)F
!pubchem_cid	42642645
!cell_type	BT474-J4 (acquired lapatinib-resistance) HER2+ breast cancer cells
!organism	human
!end_metadata
RPL34	-0.231714
COX2	-0.200375
RPL35	-0.183595
LASP1	-0.164857
NDUFS6	-0.149793
RPL8	-0.145314
TMA7	-0.144716
FTH1P5	-0.143846
RPS3	-0.138957
RPS10	-0.135044
PSMB3	-0.120517
RPLP0	-0.120516
TFF1	-0.115236
RPSA	-0.114888
TMSB10	-0.112963
EEF1A1	-0.112518
HSP90AA1	-0.112436
RPL9	-0.110249
RPS3A	-0.108664
RPS18	-0.108230
RPL30	-0.106004
COX1	-0.102604
TPT1	-0.102535
PPIA	-0.101029
NGFRAP1	-0.100808
EEF1G	-0.098834
UBB	-0.098533
MRFAP1	-0.095695
RPL21	-0.095125
RPS2	-0.092986
MYL12B	-0.092639
RPS20	-0.091642
RPS4X	-0.091596
RPL23A	-0.089959
UBC	-0.088983
TUBA1B	-0.084272
HMGN2	-0.082941
RPL41	-0.082530
RPS16	-0.079978
HMGB1	-0.078451
RPL17	-0.076664
MIEN1	-0.076498
RPS26	-0.074370
USMG5	-0.073705
RPL13A	-0.071560
RPS24	-0.070568
RPS17	-0.069314
RPL32	-0.069127
RPS27	-0.068341
RPS25	-0.066744
FAU	-0.066737
FTH1	-0.066595
COX7A2	-0.066572
PTMA	-0.065497
RPL36A	-0.064631
RPLP1	-0.063952
RPL23	-0.063311
RPS13	-0.061518
SCGB2A2	-0.061459
NDUFB9	-0.061182
MIF	-0.060675
RPL6	-0.060515
RPS23	-0.059983
CYFIP1	-0.059258
RPL28	-0.058904
RPS9	-0.058735
RPS8	-0.058658
ALDOA	-0.058357
CCT3	-0.058332
RPS11	-0.058107
RPS29	-0.057611
ATP5I	-0.056817
RPS12	-0.056511
UBA52	-0.055824
RPS19	-0.055815
KRT19	-0.053752
CHCHD2	-0.053656
ACTG1	-0.053276
RPL19	-0.053193
RPL7A	-0.052257
COX4I1	-0.051743
RPL13	-0.051700
RPL27A	-0.050297
CD24	-0.050264
RPS7	-0.050237
RPL27	-0.050091
RPL12	-0.049722
EEF1D	-0.048735
SET	-0.048570
RPL10A	-0.048119
RPS15	-0.047832
HSPA8	-0.047598
EPCAM	-0.047584
MYL6	-0.047043
PEBP1	-0.045008
RPS27A	-0.044356
RPL3	-0.043516
PARK7	-0.042747
GAPDH	-0.042734
CFL1	-0.042524
SAT1	-0.042119
OPHN1	-0.042074
TUBA1C	-0.040292
ACTB	-0.040215
RPL38	-0.040125
RPL37A	-0.040119
RPL4	-0.039758
RPL24	-0.039536
YWHAB	-0.039404
RPL7	-0.039371
NDUFA4	-0.039282
CDIPT	-0.039200
IRX3	-0.039191
RPL5	-0.038481
KRT18	-0.037908
HSPA1A	-0.037697
NPM1	-0.037631
SOD1	-0.037563
TSPAN13	-0.037540
PTP4A2	-0.036949
ATP5G1	-0.036943
COX8A	-0.036889
SUMO2	-0.036428
JTB	-0.036345
COX6C	-0.036341
COLCA1	-0.036069
LPCAT1	-0.036055
H2AFZ	-0.035984
YWHAQ	-0.035891
SKP1	-0.035262
COX6B1	-0.035130
NDUFA13	-0.035046
RPS15A	-0.034658
PFDN4	-0.034235
PABPC3	-0.033850
UQCR11	-0.033392
MAGED1	-0.033067
CD63	-0.032707
RPS21	-0.032683
WDR34	-0.032637
RAB13	-0.032481
ATP5A1	-0.032373
S100A16	-0.032330
RPS14	-0.031781
VCP	-0.030658
RPL22	-0.030043
CLTC	-0.029350
RPL15	-0.029302
SNHG5	-0.029248
MLPH	-0.029184
ANP32B	-0.028878
GGCT	-0.028147
TUBB2A	-0.027661
NDUFA3	-0.027651
MED1	-0.027560
ND6	-0.027539
EDF1	-0.027312
PRDX1	-0.026998
YWHAG	-0.026893
HNRNPA1	-0.026504
SEPW1	-0.026388
NDUFV1	-0.026370
CALM2	-0.026000
EEF1B2	-0.025986
SNRPE	-0.025776
S100A13	-0.025692
ATP5L	-0.025643
KARS	-0.025217
RPS28	-0.025190
RRM2	-0.025188
MALAT1	-0.025172
HUWE1	-0.025169
MDH2	-0.025090
PSMD3	-0.025001
CLIC1	-0.024991
S100P	-0.024985
RPL29	-0.024959
EIF3L	-0.024935
HIF1A	-0.024909
UQCRH	-0.024725
HSPD1	-0.024720
RPN2	-0.024663
ENDOG	-0.024242
DAZAP1	-0.024229
ITM2B	-0.024190
LAPTM4A	-0.024115
IER2	-0.023949
CCNI	-0.023853
RAE1	-0.023622
COX7B	-0.023365
RPL11	-0.023315
PRDX2	-0.023273
PRR11	-0.023176
TBCA	-0.023097
C1orf43	-0.022884
PSMA4	-0.022849
HIST1H4C	-0.022798
TCEB2	-0.022648
PRSS23	-0.022563
ARPC3	-0.022535
PRPF19	-0.022326
CUTA	-0.022323
C19orf43	-0.022212
NOP58	-0.022087
UQCRC1	-0.022053
SNRPD3	-0.022000
PSMB2	-0.021975
TFF3	-0.021928
KANSL1	-0.021656
EIF3H	-0.021389
HDGF	-0.021247
PRDX4	-0.021163
CISD3	-0.021146
MRPS18B	-0.020834
MGP	-0.020648
CAMLG	-0.020530
STOML2	-0.020507
H2AFJ	-0.020372
SEPHS2	-0.020319
SCGB1D2	-0.020289
HMGN1	-0.020278
RPL18	-0.020169
CCND1	-0.020101
MAL2	-0.020033
RPL35A	-0.020027
CALR	-0.019910
NACAP1	-0.019906
SNRPG	-0.019848
CBX3	-0.019731
MORF4L2	-0.019730
TSPO	-0.019626
GSS	-0.019541
MT2A	-0.019510
RAC1	-0.019324
NME1	-0.019321
AGR2	-0.019242
MEA1	-0.019230
RPS5	-0.019214
OAZ1	-0.019085
STARD3	-0.019078
MRPS21	-0.018687
MRPS24	-0.018652
NDUFB11	-0.018585
PCNA	-0.018579
LDHB	-0.018559
PSMC1	-0.018543
CANT1	-0.018440
TCEAL4	-0.018431
NDUFB1	-0.018417
UQCRB	-0.018381
SNF8	-0.018333
RPL14	-0.018327
UFC1	-0.018295
POLR2H	-0.018225
JUP	-0.018156
EIF3E	-0.018092
CCT6A	-0.018076
FBL	-0.018054
UQCRQ	-0.018039
SSR4	-0.017958
DUT	-0.017825
COX5A	-0.017619
MARCKSL1	-0.017603
SERF2	-0.017435
BTBD1	-0.017423
GDI2	-0.017399
ADIRF	-0.017347
RPL37	-0.017288
HOXB7	-0.017235
RPL10	-0.017141
PSMB4	-0.017033
PRDX6	-0.016829
F11R	-0.016647
GUK1	-0.016529
NUPR1	-0.016524
IMP4	-0.016382
BRI3BP	-0.016379
PRDX5	-0.016197
RAB1B	-0.016174
MRPL27	-0.016103
KDELR1	-0.015956
COX5B	-0.015841
TSTD1	-0.015812
TUBA1A	-0.015797
CDH1	-0.015691
HMGN3	-0.015685
ATP5E	-0.015631
PSMD2	-0.015437
GARS	-0.015425
SRP14	-0.015328
PET100	-0.015215
FIS1	-0.015198
TRMT112	-0.014878
PSME2	-0.014875
TAX1BP3	-0.014787
ARPC5L	-0.014530
SEC61G	-0.014474
TXNL1	-0.014283
RPL22L1	-0.014237
HINT1	-0.014069
TMED9	-0.014026
AFG3L2	-0.014006
BTF3	-0.013957
ECHS1	-0.013934
PSMB1	-0.013929
VAPA	-0.013896
TMEM258	-0.013886
NBL1	-0.013870
MZT2A	-0.013804
MTCH1	-0.013729
EEF1A2	-0.013718
RRM1	-0.013707
C17orf96	-0.013634
DCXR	-0.013492
SLIRP	-0.013447
KPNB1	-0.013442
RPS19BP1	-0.013313
NOP56	-0.013287
MORF4L1	-0.013254
RACGAP1	-0.013174
PPIB	-0.012982
PIGU	-0.012964
SHISA5	-0.012847
RPLP2	-0.012814
RBBP7	-0.012800
COX7C	-0.012750
ATP5J	-0.012730
PPP2R4	-0.012722
EIF4A1	-0.012719
G6PD	-0.012716
MRPL12	-0.012658
PGAP3	-0.012598
TXN	-0.012503
SEC62	-0.012441
ANXA11	-0.012440
LAMP1	-0.012350
NQO1	-0.012311
PGAM1	-0.012301
NDUFS8	-0.012247
CCAR1	-0.012235
PABPC1	-0.012216
BZW2	-0.012202
MTMR12	-0.012163
IGFBP4	-0.012150
HNRNPUL1	-0.012100
TRMT5	-0.012076
EIF6	-0.012072
MINOS1	-0.012001
ADAR	-0.011862
MANF	-0.011836
PSMG3	-0.011823
VPS51	-0.011786
GLTSCR2	-0.011738
DNAJC1	-0.011626
MKNK2	-0.011597
BUD31	-0.011477
RPS14P3	-0.011391
HSBP1	-0.011367
SUB1	-0.011345
UBE2Z	-0.011260
HIGD1A	-0.011176
POMP	-0.011168
PSMB7	-0.011104
ARPC2	-0.011091
PSMB6	-0.011088
NUCKS1	-0.011071
SFN	-0.011067
LARS	-0.010990
UBL5	-0.010962
EIF3K	-0.010955
EIF3B	-0.010931
POLR2L	-0.010908
IER3	-0.010884
TXNL4A	-0.010883
AURKA	-0.010882
POLD2	-0.010881
PFDN5	-0.010851
ATF4	-0.010805
TNPO1	-0.010798
AP2S1	-0.010667
VDAC3	-0.010650
SNRPB2	-0.010618
FTSJ2	-0.010578
GPX4	-0.010544
EEF2	-0.010534
RPL31	-0.010528
H2AFY	-0.010527
BCAP31	-0.010466
FOXO6	-0.010423
PTGES3	-0.010416
CHMP4A	-0.010389
EME1	-0.010364
FH	-0.010341
CCT5	-0.010312
MRPL51	-0.010291
PSMA7	-0.010179
EIF4G2	-0.010150
MCM7	-0.010126
DSTN	-0.010065
CKS1B	-0.010052
GALNT7	-0.010045
LINC01420	-0.010032
TUBB4B	-0.010004
NCL	-0.010003
SDC1	-0.009995
NAA10	-0.009938
TUBA4A	-0.009919
NDUFB8	-0.009877
TMED2	-0.009798
CHSY1	-0.009762
EIF3D	-0.009752
TWIST1	-0.009741
DYNLRB1	-0.009736
SNHG19	-0.009690
UFD1L	-0.009636
CSRP1	-0.009614
PPDPF	-0.009581
ADPRHL2	-0.009574
CSE1L	-0.009570
SRPRB	-0.009540
SLC25A5	-0.009503
PAF1	-0.009489
GDI1	-0.009484
ZNF562	-0.009461
OCIAD2	-0.009433
HNRNPH1	-0.009387
PHLDA2	-0.009318
NANS	-0.009310
SEC16A	-0.009305
SUPT5H	-0.009291
PLK2	-0.009288
TRAPPC5	-0.009252
ATP6	-0.009160
UCP2	-0.009128
TPM3	-0.009078
LRRFIP1	-0.009072
NTMT1	-0.009017
MRPL14	-0.009010
LUC7L3	-0.009001
GOLGA2	-0.008990