!direction	-1
!num_genes	359
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Tretinoin
!smiles	CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CC(=O)O)C)C
!drugbank_id	DB00755
!pubchem_cid	444795
!cell_type	ME180 squamous cell carcinoma cell line - 6 hours 10μM
!organism	human
!end_metadata
HPGD	-0.053666
EPB41L3	-0.052242
MT4	-0.045369
SAMD9	-0.044272
TCHHL1	-0.042838
TNFSF10	-0.040812
SCD	-0.039567
ATP7A	-0.039416
KLHL24	-0.037288
STXBP3	-0.036984
CEP70	-0.036581
CYP26A1	-0.036306
SDPR	-0.035907
KRT1	-0.035596
ACAP2	-0.035456
TMED10	-0.035344
PCMTD1	-0.035327
XRN1	-0.034163
DSG1	-0.033326
TBL1XR1	-0.032668
APOD	-0.032570
CHD9	-0.032518
KTN1	-0.032354
DAAM1	-0.031901
KRT84	-0.031680
MOB3B	-0.031600
SCOC	-0.031358
LIN54	-0.031319
DOCK8	-0.031245
KIF20B	-0.031214
FOXN2	-0.031139
SC5D	-0.030790
MIS18BP1	-0.030735
MTBP	-0.030730
FAM102B	-0.030555
PELI2	-0.030375
PLA2G4F	-0.030285
TMEM123	-0.030249
CENPF	-0.029939
LPAR6	-0.029732
ASF1A	-0.029587
CENPE	-0.029200
ZNF770	-0.029174
HLTF	-0.029045
SMARCAD1	-0.029019
NRIP1	-0.028909
NFE2L2	-0.028908
LPIN1	-0.028861
MKLN1	-0.028856
COBLL1	-0.028485
CDK19	-0.028361
SHOC2	-0.028299
KLF9	-0.028132
U2SURP	-0.028078
PTAR1	-0.027914
RB1CC1	-0.027894
HMMR	-0.027890
DLGAP5	-0.027884
RPTN	-0.027838
ATAD2	-0.027753
ASPM	-0.027638
TTK	-0.027512
KIF14	-0.027185
ABCA1	-0.027145
TP53INP1	-0.026955
ANLN	-0.026933
LSM8	-0.026879
TRIM2	-0.026846
COG6	-0.026810
PUS7L	-0.026744
FAM214A	-0.026731
SERPINB13	-0.026707
HMOX1	-0.026693
TTC37	-0.026608
TGFB3	-0.026598
TOP2A	-0.026542
CKAP2	-0.026482
STAT4	-0.026426
SNX2	-0.026315
CCDC14	-0.026293
PTBP3	-0.026204
PDCD4	-0.026102
ZNF845	-0.026090
PCM1	-0.026058
CYP26B1	-0.026015
TRAPPC8	-0.026005
NRG4	-0.025975
ORC3	-0.025966
PCMTD2	-0.025832
CEP44	-0.025702
VCPIP1	-0.025626
PRUNE2	-0.025551
TRIM31	-0.025473
MPHOSPH9	-0.025460
KLHL9	-0.025384
CUL5	-0.025379
OSTM1	-0.025349
SNRK	-0.025319
NEK1	-0.025308
CKAP2L	-0.025289
RBM47	-0.025275
ANXA2R	-0.025268
KIF11	-0.025240
IGF2BP3	-0.025234
PHIP	-0.025094
CXADR	-0.025022
ARHGAP20	-0.025010
ZNF260	-0.025009
PUM2	-0.025005
TTC14	-0.024993
SNX4	-0.024985
GNA13	-0.024985
ZNF680	-0.024964
HIF1A	-0.024940
ATP10B	-0.024937
TRIP11	-0.024885
PABPC4L	-0.024875
SCAPER	-0.024758
CLCA2	-0.024735
SLC39A2	-0.024710
RALGAPA1	-0.024648
DOCK11	-0.024636
DOPEY1	-0.024568
LOC100129550	-0.024542
RTP4	-0.024532
UBL3	-0.024500
NDFIP1	-0.024448
CXorf57	-0.024391
IFT74	-0.024357
PLS1	-0.024340
ZMYM4	-0.024339
CNTRL	-0.024306
ANKRD12	-0.024299
PIK3C2A	-0.024255
RB1	-0.024214
ZBTB33	-0.024169
DEK	-0.024046
GMFB	-0.024008
ZNF484	-0.023993
RBM27	-0.023976
CD200R1	-0.023963
TAF2	-0.023952
CPNE3	-0.023915
IGFBP5	-0.023912
MTX3	-0.023844
NEMF	-0.023835
LANCL1	-0.023833
KIF5B	-0.023796
BAZ2B	-0.023734
PAFAH1B1	-0.023734
ZMYM1	-0.023653
ZNF518B	-0.023642
RAPGEF5	-0.023585
PREPL	-0.023523
REEP3	-0.023445
EGFL6	-0.023401
RAB8B	-0.023380
CA2	-0.023324
CEP128	-0.023315
PAPD4	-0.023304
PELI1	-0.023261
TLE4	-0.023254
DENND4C	-0.023218
EFCAB14	-0.023159
ZBTB21	-0.023154
HOXA13	-0.023139
MYO9A	-0.023101
PGM2	-0.023080
RAB18	-0.023026
BLM	-0.022910
PSG5	-0.022849
KAL1	-0.022829
AKAP11	-0.022802
RPA3OS	-0.022801
TMTC3	-0.022790
KNTC1	-0.022736
MAL	-0.022717
RAI14	-0.022710
MARCH7	-0.022696
TOP2B	-0.022649
BCO1	-0.022616
ARL6IP5	-0.022598
METTL7A	-0.022586
GOLGA4	-0.022537
SPG11	-0.022488
ARID2	-0.022435
NDC80	-0.022402
BMPR2	-0.022393
JAK2	-0.022377
ZNF614	-0.022369
CYBRD1	-0.022359
ZFX	-0.022358
HSDL2	-0.022333
SUZ12	-0.022325
CAT	-0.022320
GPSM2	-0.022282
OXR1	-0.022280
ZSCAN31	-0.022277
FAM76B	-0.022255
C5orf51	-0.022241
TBK1	-0.022220
KIAA1551	-0.022142
NUSAP1	-0.022042
CEP55	-0.022029
ZNF518A	-0.022005
GHR	-0.021979
FAR1	-0.021884
ZNF148	-0.021877
CENPK	-0.021863
PDS5B	-0.021856
ELF1	-0.021836
CXorf28	-0.021817
PAPOLA	-0.021784
MAFB	-0.021772
ATF7IP2	-0.021772
MAP4K5	-0.021769
PDIK1L	-0.021730
FAM49A	-0.021701
RP2	-0.021691
CHURC1	-0.021672
PDGFD	-0.021657
MAP4K3	-0.021639
NCAPG	-0.021571
ELOVL6	-0.021560
TBC1D31	-0.021551
CAP2	-0.021551
CAND1	-0.021531
CCP110	-0.021512
PARP14	-0.021491
VMA21	-0.021480
SNX13	-0.021422
TXNDC16	-0.021412
AHI1	-0.021406
XPO1	-0.021338
HECTD1	-0.021320
SKAP2	-0.021286
ZHX1	-0.021274
AEBP2	-0.021256
SNCAIP	-0.021232
JMJD1C	-0.021191
KCTD3	-0.021160
RAB22A	-0.021154
UBXN4	-0.021123
RBM25	-0.021104
GLTP	-0.021028
CD2AP	-0.021028
DIP2B	-0.021009
IFIT2	-0.020975
DTX3L	-0.020972
C2CD5	-0.020958
RAP2A	-0.020910
DPY19L4	-0.020886
FA2H	-0.020862
SLMAP	-0.020835
ECT2	-0.020833
PCF11	-0.020828
FZD6	-0.020815
PJA2	-0.020808
SSR1	-0.020802
ANKIB1	-0.020802
NBN	-0.020780
SECISBP2L	-0.020774
RDX	-0.020703
AMOT	-0.020685
CUL2	-0.020681
MAP3K8	-0.020619
GCA	-0.020576
CEP152	-0.020575
GPNMB	-0.020571
HELZ	-0.020549
MYLIP	-0.020543
AGGF1	-0.020532
SLC30A7	-0.020524
CPD	-0.020520
ARSK	-0.020461
VTA1	-0.020430
DDIAS	-0.020421
USPL1	-0.020354
LCOR	-0.020335
RALGPS1	-0.020297
DSG3	-0.020259
MORC3	-0.020247
TLR3	-0.020241
NAB1	-0.020238
CERS6	-0.020218
RAB10	-0.020209
DHX29	-0.020208
TTC33	-0.020158
TMX3	-0.020146
C10orf99	-0.020117
CASC5	-0.020100
SMC2	-0.020083
C5orf24	-0.020071
RGPD8	-0.020070
CENPQ	-0.020026
TOPBP1	-0.020008
NPR3	-0.020006
YTHDC2	-0.019981
WDFY1	-0.019941
UBE2Q2	-0.019940
INSIG1	-0.019924
IDH1	-0.019866
CEP192	-0.019858
NKTR	-0.019843
UBLCP1	-0.019807
PLK4	-0.019798
FAM111A	-0.019774
PPWD1	-0.019770
FAM117B	-0.019733
VAMP7	-0.019730
KIDINS220	-0.019716
CLDND1	-0.019681
DNAJC13	-0.019654
NREP	-0.019638
C4orf33	-0.019626
CSTF2T	-0.019608
CYSRT1	-0.019606
SLC30A10	-0.019575
PIGK	-0.019564
SIPA1L2	-0.019563
DEPDC1B	-0.019563
TAX1BP1	-0.019554
LRRC58	-0.019552
HCAR2	-0.019540
CTDSPL2	-0.019539
CCDC15	-0.019522
BMI1	-0.019521
ANKRD50	-0.019512
ITGAV	-0.019498
ARL5B	-0.019495
KBTBD8	-0.019481
RIF1	-0.019421
STAU2	-0.019418
SMEK2	-0.019387
C3orf58	-0.019384
IBTK	-0.019376
SMC6	-0.019373
LTN1	-0.019339
FUBP3	-0.019328
CNTLN	-0.019321
EML4	-0.019308
KIT	-0.019305
KRTDAP	-0.019269
EPM2AIP1	-0.019259
NPAT	-0.019237
CBR4	-0.019223
C6orf15	-0.019219
SCNN1A	-0.019218
CEP135	-0.019188
STX19	-0.019176
FRMD6	-0.019168
CSE1L	-0.019165
TRIM22	-0.019144
SEMA4D	-0.019136
NMRK1	-0.019135
MAP3K1	-0.019118
NETO2	-0.019106
PTPLB	-0.019039
MXRA5	-0.019009