!direction	-1
!num_genes	285
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	curcumin
!smiles	COC1=C(C=CC(=C1)C=CC(=O)CC(=O)C=CC2=CC(=C(C=C2)O)OC)O
!pubchem_cid	969516
!cell_type	U937 monoctyes exposed to oxidative stress - 4 Hours
!organism	human
!end_metadata
NDUFA1	-0.133721
LYZ	-0.124553
CAPG	-0.113029
CXCL10	-0.107969
TYROBP	-0.107842
ALOX5AP	-0.102628
CCL1	-0.101734
TPSB2	-0.097307
HMOX1	-0.089594
S100A9	-0.088080
RPL34	-0.083942
BCAP31	-0.083246
RPS14P3	-0.078507
S100A11	-0.073977
SHFM1	-0.071693
RSAD2	-0.069092
HIF1A	-0.067451
PCBP1	-0.062559
GPX1	-0.062248
FABP4	-0.062024
UQCRH	-0.061810
SRP14	-0.060467
SEC11A	-0.059672
IFIT2	-0.059341
ISG20	-0.057493
PSMA4	-0.056933
PRDX1	-0.056341
NPC2	-0.055973
PPIB	-0.055446
MMP9	-0.054397
CCL5	-0.053996
S100A8	-0.053035
SOD2	-0.052939
PSAP	-0.051374
TPSAB1	-0.050809
RPL12	-0.050358
SEC61G	-0.050156
TM9SF2	-0.049781
TBCA	-0.049510
FAU	-0.049310
OST4	-0.048909
LDHA	-0.048345
TMBIM6	-0.045923
CHIT1	-0.044805
CXCL11	-0.044636
PSMD14	-0.043999
SSR4	-0.043592
SLC7A7	-0.043230
CHCHD2	-0.042390
ERH	-0.042318
RPL35	-0.041459
TALDO1	-0.041128
TMEM258	-0.040756
TAP1	-0.039407
IL6	-0.039013
NKG7	-0.038948
APOC2	-0.038184
HLA-A	-0.038134
ARF4	-0.037446
FCGR2B	-0.036793
NDRG1	-0.036708
HLA-G	-0.036671
HSPB1	-0.036293
ATP6V0B	-0.036246
IFI44L	-0.036206
CES1	-0.036173
IFI27	-0.035984
IFITM1	-0.035971
TNFAIP6	-0.035917
TNFSF10	-0.035666
FFAR2	-0.035636
SNHG6	-0.035581
ISCU	-0.035394
ARL6IP1	-0.035164
NQO1	-0.034768
TDP2	-0.034579
IRS2	-0.034433
ARL6IP5	-0.034186
TM2D2	-0.033708
DAD1	-0.033406
TMEM158	-0.033187
SAT1	-0.033030
GADD45B	-0.032763
MRFAP1	-0.032752
PDK1	-0.032448
SF3B5	-0.032348
RPL24	-0.032264
COX7C	-0.032195
MORF4L1	-0.032159
TNFSF13B	-0.031933
NDUFA4	-0.031917
BLOC1S2	-0.031403
PROCR	-0.031132
PSMD8	-0.030836
SNX3	-0.030827
TMA7	-0.030625
S100A10	-0.030234
RPL6	-0.029691
PSMB3	-0.029580
GAS5	-0.029367
UBA52	-0.029299
SUGT1	-0.029237
SPPL2A	-0.029196
TMEM230	-0.028953
TRAM1	-0.028858
PFKFB3	-0.028702
CD63	-0.028697
SNRPD2	-0.028632
SELK	-0.028590
IL4I1	-0.028524
TKT	-0.028494
MMP12	-0.028421
SCP2	-0.028209
ABRACL	-0.028135
IL7R	-0.028013
PTTG1IP	-0.027989
EIF3H	-0.027622
EIF3I	-0.027567
BZW1	-0.027535
RPL10A	-0.027265
TXNIP	-0.027087
MYL12A	-0.027063
SNHG1	-0.027003
RPS29	-0.026753
GBE1	-0.026684
NACAP1	-0.026575
CXCL6	-0.026564
VIMP	-0.026424
KDELR2	-0.026415
FCGR2C	-0.026399
ATP5J	-0.026118
CTSD	-0.025957
RPL11	-0.025955
SRGN	-0.025608
HSPE1	-0.025492
EIF5	-0.025460
PPIF	-0.025430
TUBA4A	-0.025394
CD163	-0.025296
MGLL	-0.025291
TRMT112	-0.025168
MXD1	-0.024898
TPM4	-0.024536
HSPA6	-0.024488
TXN	-0.024453
NCF1C	-0.024339
HNRNPC	-0.024014
UXT	-0.023968
RPL23	-0.023920
TCEB2	-0.023731
MMP8	-0.023692
ARPC5	-0.023590
EMC4	-0.023482
TPD52L2	-0.023319
CHSY1	-0.023249
ZFAS1	-0.023143
CLIC1	-0.023089
RCBTB2	-0.022873
PDIA6	-0.022756
MTCH1	-0.022727
OLIG1	-0.022555
UBL5	-0.022511
GPNMB	-0.022406
TAF7	-0.022392
SRSF2	-0.022288
LYN	-0.022021
DYNLT1	-0.021974
HCAR3	-0.021954
GABARAP	-0.021934
HSP90B1	-0.021729
LAPTM4A	-0.021699
CD14	-0.021697
SLA	-0.021692
RABAC1	-0.021676
LY6E	-0.021643
RPS27L	-0.021629
ERP29	-0.021596
PSMA6	-0.021555
TOR1B	-0.021540
OSTC	-0.021493
ADI1	-0.021489
LAMP2	-0.021396
RGS16	-0.021378
PLAU	-0.021338
FAM96A	-0.021278
ETFA	-0.021264
CORO1C	-0.021164
TMED2	-0.021128
CLEC2B	-0.020915
SERP1	-0.020850
NPTN	-0.020776
HEXA	-0.020712
ADM	-0.020666
SNRPG	-0.020557
MORF4L2	-0.020469
HLA-F	-0.020444
GM2A	-0.020440
RPS26	-0.020258
VKORC1	-0.020073
MMP3	-0.020066
EMR1	-0.020037
ATP6V1E1	-0.020013
SERF2	-0.020007
FXYD5	-0.019995
MAN2B1	-0.019931
LYSMD2	-0.019847
PSMD11	-0.019841
OLR1	-0.019627
CD99	-0.019564
EIF4A2	-0.019558
PNN	-0.019534
CXCR4	-0.019516
PRDX5	-0.019421
EEF1D	-0.019341
ITM2B	-0.019135
CXCL3	-0.019095
MIR22HG	-0.019009
FUCA2	-0.018776
GBP1	-0.018775
FN1	-0.018693
GPR183	-0.018614
RPL36	-0.018550
TMCO1	-0.018472
MOB4	-0.018447
TRIM22	-0.018443
PSMB4	-0.018437
MIR21	-0.018385
RILPL2	-0.018272
HCK	-0.018223
EMP1	-0.018169
TXNDC12	-0.018090
SEC61B	-0.018052
C20orf24	-0.017973
ATP5J2	-0.017919
RAB13	-0.017886
PSMA3	-0.017798
LOC100129361	-0.017747
RNF149	-0.017740
SNX10	-0.017694
TMED3	-0.017573
MRPL32	-0.017563
SAMD9	-0.017563
CPOX	-0.017526
SRPK1	-0.017506
PSMB1	-0.017451
ASAH1	-0.017427
ATP6V0D2	-0.017379
NACA	-0.017355
C16orf54	-0.017347
HPCAL1	-0.017264
BAMBI	-0.017259
PSMC6	-0.017239
EID1	-0.017202
ATP6V1F	-0.017142
TOP1	-0.017140
TMEM14B	-0.017134
NAP1L1	-0.017125
DUSP10	-0.017121
ENC1	-0.017116
COPS5	-0.017090
C3AR1	-0.017062
USP18	-0.016941
RPS6	-0.016881
DBI	-0.016716
DNAJA1	-0.016707
SNRPC	-0.016648
MRPS24	-0.016635
GPR34	-0.016629
RSRC2	-0.016625
IFI44	-0.016526
UBE2Z	-0.016517
RPS21	-0.016441
CD163L1	-0.016415
GNA15	-0.016281
COX5B	-0.016234
MLKL	-0.016206
SOD1	-0.016106
UPP1	-0.016053
MMP10	-0.016038
ATP5I	-0.016019
EIF2S1	-0.016008
GLB1	-0.015989
SF3B6	-0.015980
AGPAT9	-0.015960
KARS	-0.015879