!direction	-1
!num_genes	284
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!drug_name	Temozolomide
!smiles	CN1C(=O)N2C=NC(=C2N=N1)C(=O)N
!drugbank_id	DB00853
!pubchem_cid	5394
!cell_type	U87
!organism	human
!end_metadata
SERPINB2	-0.064385
DAPK3	-0.045732
HMOX1	-0.045414
PRR7	-0.036931
VTRNA2-1	-0.036505
PREX1	-0.035826
FLNA	-0.035028
LIF	-0.034950
IL1B	-0.034816
DUSP6	-0.034386
RNY4	-0.033791
SLC16A6	-0.033699
RNA28S5	-0.033100
AMY1C	-0.032986
GNAI2	-0.032725
ARHGDIA	-0.031992
PEBP1	-0.031205
PPP1R15A	-0.031110
SPATC1L	-0.030997
HS1BP3	-0.030823
CLCN7	-0.030760
PTGS2	-0.030726
SGTA	-0.030678
FAM210B	-0.030279
NOV	-0.029850
RND3	-0.029468
RRAGD	-0.028721
MAP1S	-0.028112
SSNA1	-0.027779
NPC1	-0.027200
IGFBP1	-0.027075
ADAMTS1	-0.027046
SYNC	-0.026857
RRP12	-0.026825
GRINA	-0.026772
SPRY2	-0.026705
AQP9	-0.026679
WBP2	-0.026538
HNRNPA3P1	-0.026366
RPS28	-0.026320
TRIM47	-0.026206
GCNT3	-0.026139
BLK	-0.026113
TRAPPC5	-0.025719
RNPEPL1	-0.025274
PPDPF	-0.025241
LOC340357	-0.025218
NDUFAB1	-0.025217
CHCHD10	-0.025046
TRUB2	-0.024681
AGTRAP	-0.024573
CEBPZ	-0.024544
SLC38A6	-0.024488
TFPI2	-0.024486
IGF2BP1	-0.024315
PNLIPRP3	-0.024268
VTI1B	-0.024214
RPS4Y1	-0.024212
C19orf70	-0.024120
RWDD2B	-0.024012
JOSD2	-0.023959
JUN	-0.023902
CLPTM1	-0.023890
MAP3K11	-0.023848
CDH4	-0.023560
TMEM223	-0.023349
CSF3	-0.023292
CHIC2	-0.023206
NAGLU	-0.023153
PLEKHO1	-0.023114
YEATS4	-0.023004
SNHG7	-0.022995
RAD23A	-0.022975
DKC1	-0.022950
RRS1	-0.022924
DIMT1	-0.022904
TBX2	-0.022855
MIR877	-0.022605
TWF2	-0.022466
PPP1R14B	-0.022466
CEND1	-0.022388
CXCL2	-0.022298
MRPL12	-0.022273
FTH1	-0.022192
EXOSC4	-0.022176
KTI12	-0.021950
MRPS30	-0.021904
APBB1IP	-0.021862
SHC3	-0.021831
GFER	-0.021734
SPOCD1	-0.021644
PPM1J	-0.021526
CRYZ	-0.021495
PAQR3	-0.021299
DAW1	-0.021265
INSIG1	-0.021231
LYSMD2	-0.021156
HSPB6	-0.021135
ERGIC1	-0.021133
PLEKHN1	-0.021114
KRT10	-0.021097
IRS1	-0.021086
SNORD19B	-0.021003
FADS3	-0.020963
NFKBIB	-0.020928
BIVM	-0.020870
PA2G4	-0.020817
LTBR	-0.020647
KIAA1522	-0.020568
FTH1P3	-0.020547
SYNCRIP	-0.020506
TMEM63B	-0.020488
IER2	-0.020482
UTP18	-0.020471
DNAH7	-0.020465
C2CD2	-0.020374
MSX1	-0.020287
QTRT1	-0.020284
PLAU	-0.020252
DHCR7	-0.020231
SIK1	-0.020195
MKL2	-0.020179
IGFBP6	-0.020068
DDX39A	-0.019996
RBM42	-0.019979
PACS1	-0.019943
PTMS	-0.019883
FCRLB	-0.019857
CCL8	-0.019823
CST3	-0.019797
YTHDF2	-0.019777
GPNMB	-0.019766
CCDC60	-0.019759
SDF2L1	-0.019758
THPO	-0.019728
MTDH	-0.019680
NRIP1	-0.019654
PRDM15	-0.019653
OR8K3	-0.019534
SLC25A13	-0.019478
TNFRSF9	-0.019442
MAP3K14	-0.019440
MT1M	-0.019401
GPR135	-0.019374
MIR1282	-0.019324
DUSP5	-0.019323
EMP3	-0.019297
MMP1	-0.019280
STAC2	-0.019261
THBS3	-0.019237
PTPMT1	-0.019196
MIR578	-0.019185
SRM	-0.019140
TPM4	-0.019135
PEPD	-0.019130
TBC1D17	-0.019081
TRMT1	-0.019071
RPS19BP1	-0.019045
ARC	-0.018987
TAOK1	-0.018971
EHBP1L1	-0.018953
CLN3	-0.018930
TARS	-0.018896
CCDC124	-0.018892
MMP3	-0.018856
LOC100130093	-0.018848
MIR658	-0.018822
KPNB1	-0.018811
COPG2	-0.018803
CCDC107	-0.018765
KIAA0196	-0.018755
POLR3D	-0.018755
CAMTA2	-0.018714
MTA1	-0.018705
C19orf60	-0.018692
VAT1	-0.018690
TNC	-0.018686
HKDC1	-0.018677
C17orf74	-0.018662
METRN	-0.018635
ZNF593	-0.018614
EHD1	-0.018613
HSPBP1	-0.018550
DNAJC5G	-0.018544
EMC2	-0.018544
KRT36	-0.018538
ALKBH7	-0.018512
PTGES	-0.018473
CNTNAP3	-0.018468
U2AF1	-0.018443
SLC11A2	-0.018362
PKHD1L1	-0.018342
ANKRD34A	-0.018331
KRT75	-0.018276
SPNS3	-0.018175
NDUFB10	-0.018148
MAP2K2	-0.018146
PCDHGA12	-0.018132
SLC35E4	-0.018130
LOC283332	-0.018099
DOK1	-0.018051
ACTN4	-0.018035
HSD17B14	-0.018021
ESRRA	-0.018020
RERG-AS1	-0.017996
GRAMD2	-0.017994
DNAJC24	-0.017975
TTYH3	-0.017952
GSTO1	-0.017940
PPP6R1	-0.017928
MYO1F	-0.017901
TGM4	-0.017854
FAM86HP	-0.017829
STX4	-0.017792
ABHD5	-0.017784
KCTD8	-0.017751
NFIX	-0.017727
PRKAR1B	-0.017725
RAB3IL1	-0.017723
MIR1185-1	-0.017648
AP5S1	-0.017642
PTDSS2	-0.017639
FAM214B	-0.017609
VPS4A	-0.017556
GRHPR	-0.017551
RPS6KA4	-0.017502
CFP	-0.017476
TSR3	-0.017475
MRPL15	-0.017460
TMUB1	-0.017447
ENDOG	-0.017431
MBOAT7	-0.017384
TMEM192	-0.017302
CAGE1	-0.017293
TRPC4	-0.017293
CBX1	-0.017253
LINC00200	-0.017212
TATDN1	-0.017205
MRPL34	-0.017194
AGK	-0.017175
MGAT4B	-0.017155
USF2	-0.017122
KARS	-0.017093
MSANTD3	-0.017052
NSFP1	-0.017050
ZCCHC9	-0.017033
ARHGEF5	-0.017031
KRTAP1-5	-0.017028
FAM86C1	-0.017026
SERPINE1	-0.017017
BRF2	-0.017013
TNP2	-0.016990
IMP4	-0.016985
ADAMTS15	-0.016970
LOC100128573	-0.016961
ARL8B	-0.016946
CYBA	-0.016923
TRIM51	-0.016916
MITD1	-0.016912
CBX5	-0.016903
FGF2	-0.016899
TDRP	-0.016896
GGT3P	-0.016886
CALR	-0.016844
C1QBP	-0.016829
FADD	-0.016819
TAL2	-0.016793
BUB1B	-0.016793
CHST10	-0.016761
ST8SIA2	-0.016743
ZNF768	-0.016727
COPB1	-0.016724
UBALD1	-0.016721
SH3BP5L	-0.016716
DHX30	-0.016694
SAT2	-0.016681
PAPPA	-0.016680
PRDM13	-0.016640
TMEM89	-0.016639
MIR609	-0.016635
BRI3	-0.016628
SCAF1	-0.016626
SLC31A1	-0.016613
CRIP3	-0.016580