!direction	-1
!num_genes	298
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Morphine
!smiles	CN1CCC23C4C1CC5=C2C(=C(C=C5)O)OC3C(C=C4)O
!drugbank_id	DB00295
!pubchem_cid	5288826
!cell_type	Striatum - 129P3/J mice - Chronic morphine treatment
!organism	mouse
!end_metadata
TTR	-0.334171
CST3	-0.129251
PFDN6	-0.110779
FAM71F1	-0.088765
NNAT	-0.087790
TUSC2	-0.075585
CA2	-0.074498
PSAP	-0.071709
FABP7	-0.069298
ZIC1	-0.069271
RPS15	-0.069234
PLP1	-0.067114
APOE	-0.066907
ADORA2A	-0.065951
GNG7	-0.065282
CALR	-0.061923
BSG	-0.061778
PCP4	-0.060491
ID4	-0.059023
ZCCHC12	-0.059013
RPS12	-0.058063
CNP	-0.056741
CKB	-0.056563
TMA7	-0.056437
CTRB2	-0.055990
SP4	-0.055642
WFIKKN1	-0.055466
RPL26	-0.050143
TUBB2B	-0.050122
HSPA5	-0.049344
RPL4	-0.049204
RPL3	-0.048986
LOC728392	-0.048670
SYNPR	-0.048460
FABP5	-0.047690
QDPR	-0.047013
PDE1B	-0.046648
HIST1H1C	-0.046300
TMEM130	-0.046288
TFG	-0.045886
RNF145	-0.045118
GSTP1	-0.044713
RPL10	-0.044645
ANKRD63	-0.044019
PLTP	-0.043686
CALB2	-0.043470
HAP1	-0.042969
HPCA	-0.042030
TIMM8B	-0.041823
B3GNT1	-0.041645
TUBA1A	-0.041300
MEIS2	-0.041140
KCNJ11	-0.040863
EFNB3	-0.040495
GJA1	-0.040490
RPL11	-0.040184
PGRMC1	-0.039814
LRRC19	-0.039800
NCDN	-0.039756
GPR17	-0.039456
HIST1H2BI	-0.039340
KLHDC1	-0.039188
IMP4	-0.039062
VAT1L	-0.038944
HMGN1	-0.038812
RPL28	-0.038719
RPL13	-0.038659
EEF1B2	-0.038465
CD81	-0.038099
PBX3	-0.037832
RPL7A	-0.037790
ELOVL2	-0.037662
LACE1	-0.037254
CHCHD10	-0.037102
HSPA8	-0.036944
ZMPSTE24	-0.036802
LGALS2	-0.036680
NDUFA1	-0.036595
FARP1	-0.036024
BAIAP3	-0.035849
RXRG	-0.035709
CACHD1	-0.035418
TRIM46	-0.035339
RPS7	-0.035070
PCSK1N	-0.034778
MANF	-0.034745
DRD2	-0.034729
OSBPL8	-0.034608
PPP1CA	-0.034507
GAP43	-0.034335
LOH12CR1	-0.034091
CTXN1	-0.034056
ARL3	-0.033814
COX6B1	-0.033507
GNB2	-0.033275
RGS10	-0.033199
SESN3	-0.033179
RPS5	-0.033124
PISD	-0.033084
FOXG1	-0.032998
SOX2	-0.032903
MAN1A1	-0.032739
GAA	-0.032732
HIST1H2BO	-0.032628
CALY	-0.032289
PRMT2	-0.032285
LZTS3	-0.032123
NGEF	-0.032095
LY6H	-0.032019
NGFRAP1	-0.032004
NAP1L5	-0.031863
ITM2C	-0.031789
NECAB2	-0.031760
CSDC2	-0.031722
CHORDC1	-0.031706
RPL27	-0.031458
RPS11	-0.031444
NREP	-0.031228
CNIH2	-0.031009
HSPH1	-0.030779
NACA	-0.030763
PCDH8	-0.030652
KCTD12	-0.030116
GPR6	-0.030004
ATP5B	-0.029948
PPAP2B	-0.029853
RPS26	-0.029553
PMP2	-0.029289
YWHAQ	-0.029072
GPR155	-0.028889
FAU	-0.028864
RPL18A	-0.028705
DNAJA1	-0.028621
ROMO1	-0.028195
ABHD3	-0.028190
GRM4	-0.027768
SPOCK3	-0.027717
GLTP	-0.027662
SYNDIG1L	-0.027496
DDN	-0.027486
MAG	-0.027404
PTPLA	-0.027280
ADAM21	-0.027274
RASL10B	-0.027257
UGGT2	-0.027000
CSF2RA	-0.026960
ELMOD1	-0.026917
DBI	-0.026898
SERPINE2	-0.026728
RPS28	-0.026624
ARL6IP5	-0.026592
ATP5J	-0.026571
ENPP2	-0.026538
COX7A2	-0.026425
RPL10A	-0.026399
CHMP4B	-0.026179
RESP18	-0.026071
TFEB	-0.026061
HMP19	-0.025947
LGMN	-0.025849
HSP90B1	-0.025721
NDN	-0.025629
MAN1A2	-0.025496
RIC8B	-0.025441
DARS2	-0.025402
ITGB1BP1	-0.025313
HSD3B1	-0.025298
ZDBF2	-0.025232
C1orf109	-0.025156
UGT8	-0.025008
MBOAT2	-0.024988
ATP5J2	-0.024949
ASIC4	-0.024948
DBP	-0.024848
YWHAE	-0.024813
SNRPD2	-0.024779
KCNJ4	-0.024779
GPR88	-0.024499
AHI1	-0.024422
GRM3	-0.024383
MIEN1	-0.024299
KIFC2	-0.024283
PNMAL2	-0.024248
BCL11B	-0.024235
APLP1	-0.024217
C14orf1	-0.024066
BHLHB9	-0.024006
PEA15	-0.023982
GPI	-0.023978
IVNS1ABP	-0.023970
PLXNB2	-0.023905
RGS2	-0.023893
COX6A1	-0.023892
BEX1	-0.023785
TMEM47	-0.023768
RPLP0	-0.023677
CCDC90B	-0.023616
TMEM185A	-0.023449
LYPD4	-0.023347
ARL6	-0.023317
RPS8	-0.023106
TMEM38B	-0.023085
XBP1	-0.023056
EIF3F	-0.023007
GPR61	-0.022983
DCLK3	-0.022950
TRAPPC2L	-0.022944
RPL6	-0.022918
PRDX1	-0.022887
HNRNPH1	-0.022837
RPL9	-0.022542
PFKFB4	-0.022427
ZIC3	-0.022377
METTL9	-0.022339
SNX14	-0.022317
EIF4A1	-0.022204
RPS23	-0.022068
PHLDB1	-0.021981
SYBU	-0.021947
RPS13	-0.021931
RPS27A	-0.021910
ASCC1	-0.021852
LRRC3B	-0.021840
TRA2A	-0.021763
BCAS1	-0.021701
NDUFV3	-0.021610
ATP2B3	-0.021589
TTI2	-0.021465
RPL23	-0.021429
KIAA1462	-0.021318
PENK	-0.021316
ECEL1	-0.021228
LRP12	-0.021207
ZFYVE19	-0.021203
GUCY1A3	-0.021169
SNRPF	-0.021162
TRIM62	-0.021003
DUSP26	-0.020918
ARPC5L	-0.020917
NDUFA4	-0.020800
KLHL7	-0.020776
HEXB	-0.020776
OLIG1	-0.020758
DNAJB2	-0.020682
EZH2	-0.020614
SNX3	-0.020587
CAP1	-0.020574
CYB5A	-0.020508
RARG	-0.020465
RSL24D1	-0.020442
FNBP1	-0.020310
SDHB	-0.020251
GAD1	-0.020224
GOLGA7	-0.020209
CMTM5	-0.020090
S100A16	-0.020076
PRKCH	-0.019961
VSTM2A	-0.019929
COQ10B	-0.019904
PPP1R1B	-0.019895
GPRC5B	-0.019882
CAT	-0.019843
SLC39A11	-0.019724
STRIP2	-0.019689
GNG10	-0.019673
TF	-0.019668
ZNHIT1	-0.019645
NDUFA7	-0.019569
PDE10A	-0.019566
SPARC	-0.019560
NOB1	-0.019497
RGS4	-0.019454
RPS2	-0.019420
TCP1	-0.019380
HSP90AB1	-0.019369
NEXN	-0.019356
RPL27A	-0.019321
UQCRB	-0.019304
NDRG2	-0.019285
HDC	-0.019234
RARB	-0.019215
TPPP	-0.019142
IFNLR1	-0.019101
FTL	-0.019094
MARCKSL1	-0.019080
CD9	-0.018953
HDAC5	-0.018866
KCNJ10	-0.018804
C2orf49	-0.018772
NDUFA13	-0.018762
NTSR2	-0.018757
ITIH3	-0.018712
MBP	-0.018658
WDR6	-0.018574
SFPQ	-0.018485
SLC6A11	-0.018479
IDO1	-0.018423
GNG4	-0.018397