!direction	-1
!num_genes	248
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	human
!drug_name	Methotrexate
!smiles	CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O
!drugbank_id	DB00563
!pubchem_cid	126941
!cell_type	granulocyte
!organism	human
!end_metadata
BTNL8	-0.132501
PCDH8	-0.065346
RNASE2	-0.064482
LOC101928893	-0.060981
RNASE3	-0.058325
FAM3B	-0.055217
KIAA1324	-0.050524
COL9A3	-0.050490
RGPD1	-0.050476
PLA2G4A	-0.039945
TMEM170B	-0.038953
ACCS	-0.038871
DDX17	-0.038843
CEP192	-0.037405
TMEM45B	-0.037252
NOD2	-0.037094
PI3	-0.036501
IDO1	-0.036480
LAP3	-0.036474
ERO1L	-0.034993
CLEC12A	-0.034917
LTF	-0.034266
IFI44L	-0.033763
GPX3	-0.033608
SLPI	-0.032997
DUT	-0.032796
HOXA5	-0.032659
CCBL2	-0.032261
MXRA7	-0.032121
P2RY14	-0.031868
RSAD2	-0.031851
DERA	-0.031586
FOLR3	-0.031583
LILRA3	-0.031315
CCR3	-0.031214
KLHL15	-0.030970
NCKAP1L	-0.030896
SERPINB9P1	-0.030740
RPA3OS	-0.030502
RAB33A	-0.030471
CMPK2	-0.030384
GPR171	-0.030186
APOBEC3B	-0.030164
SDHD	-0.029954
PPIP5K2	-0.029807
SECISBP2L	-0.029628
SLC7A7	-0.029435
GZMM	-0.029434
THBD	-0.028985
MCEMP1	-0.028946
BRI3BP	-0.028743
RAPGEF1	-0.028667
FRY-AS1	-0.028312
CD93	-0.028183
CLASRP	-0.027882
SMCO4	-0.027753
OLFM4	-0.027322
MIF	-0.027266
A2M-AS1	-0.027193
RPS26	-0.027130
LIG4	-0.027108
PSPH	-0.027087
SPP1	-0.027058
MCOLN1	-0.027020
CCRL2	-0.026851
SAMSN1	-0.026736
PITPNM1	-0.026534
CCL4	-0.026479
HPSE	-0.026436
PDZD8	-0.026425
C15orf40	-0.026404
PVRL2	-0.026334
ACADM	-0.026234
LRRC37A2	-0.026224
SLFN12	-0.026063
NPTN-IT1	-0.025966
HNRNPU-AS1	-0.025597
CD48	-0.025591
PLGLB2	-0.025538
METTL23	-0.025300
FAM177A1	-0.025259
LXN	-0.025255
GRAMD1C	-0.025231
XIST	-0.024987
TAGLN2	-0.024937
GZMK	-0.024931
HCG27	-0.024895
C10orf32	-0.024731
FLVCR1	-0.024727
ANXA5	-0.024617
NAIP	-0.024484
AREG	-0.024114
DDX60	-0.024099
MX1	-0.024091
UHRF2	-0.024023
GNA15	-0.023966
ITGAE	-0.023843
ZNF267	-0.023840
DENND4A	-0.023697
GPR183	-0.023632
SPAG1	-0.023427
ANXA4	-0.023364
CLEC4A	-0.023337
EPSTI1	-0.023284
XAF1	-0.023167
CHAC2	-0.023167
POC1B	-0.023150
CXCL6	-0.023067
TMEM154	-0.023056
TEN1	-0.022987
ZCCHC8	-0.022985
FLJ36848	-0.022829
SLC36A4	-0.022696
NMUR1	-0.022691
IFI6	-0.022599
UTS2	-0.022598
OXA1L	-0.022535
ZNF266	-0.022485
JADE1	-0.022363
DMTF1	-0.022135
MALAT1	-0.022119
SLC16A6	-0.022081
SKAP2	-0.022081
RPN2	-0.021982
GSKIP	-0.021937
HERC5	-0.021815
PDCD10	-0.021676
RNF167	-0.021621
CLPTM1	-0.021489
KLHL5	-0.021477
C19orf40	-0.021336
TAX1BP3	-0.021294
SNX16	-0.021268
ESCO1	-0.021224
PSMC6	-0.021203
LOC729839	-0.021186
CLEC1A	-0.021148
C12orf5	-0.021123
RSPH10B2	-0.021083
MED30	-0.021061
TMEM123	-0.021041
TCFL5	-0.020994
ZNF324	-0.020858
EXT2	-0.020817
ZNF654	-0.020765
BCL11A	-0.020730
ATHL1	-0.020709
AK3	-0.020692
SGMS1	-0.020622
COPB1	-0.020558
GNAI2	-0.020536
RPS6KB2	-0.020514
S100A4	-0.020500
LOC642361	-0.020450
MARCKSL1	-0.020353
HIGD1A	-0.020278
ANKRA2	-0.020179
KLRG1	-0.020177
FUZ	-0.020173
DCP1A	-0.020097
FAR2	-0.020080
ANXA6	-0.020054
RALGDS	-0.019981
MSRB2	-0.019963
SPACA6P	-0.019840
KIAA1279	-0.019828
ZNHIT3	-0.019783
KCNH1	-0.019778
GZMH	-0.019744
SLC20A1	-0.019723
RAB5C	-0.019671
ANXA1	-0.019622
ARSA	-0.019513
MICU2	-0.019430
HES4	-0.019422
LOC102724094	-0.019386
HCP5	-0.019381
GSTT1	-0.019331
XPO1	-0.019316
MARCH2	-0.019240
VAMP7	-0.019227
YBEY	-0.019217
SEP15	-0.019164
IGJ	-0.019139
RNF4	-0.019136
TMX2	-0.019111
ADAT1	-0.018968
CD8A	-0.018956
TMEM71	-0.018938
SGK3	-0.018908
SNORD89	-0.018892
ENDOG	-0.018889
RANBP2	-0.018885
TMEM200B	-0.018868
RNASE6	-0.018829
SDSL	-0.018804
DPY19L3	-0.018782
HDHD3	-0.018779
LOC100630918	-0.018709
RNFT1	-0.018659
SLBP	-0.018646
ACP5	-0.018589
YIPF5	-0.018562
OSCP1	-0.018508
PLAGL1	-0.018497
LOC403323	-0.018483
USP32P2	-0.018442
UAP1	-0.018440
HIST1H2BG	-0.018439
TBL1Y	-0.018433
CHST7	-0.018378
FAM187B	-0.018354
CIB1	-0.018332
PPIB	-0.018262
YWHAQ	-0.018262
LOC100270804	-0.018233
RGS1	-0.018198
MTFR1L	-0.018181
TMEM88	-0.018179
ZBTB48	-0.018167
CAMP	-0.018149
SACM1L	-0.018111
SYAP1	-0.018109
KLRD1	-0.018061
PER1	-0.018061
CD69	-0.018048
REV3L	-0.017969
SLC35B3	-0.017966
GNLY	-0.017954
CEBPD	-0.017926
MLH1	-0.017871
SNAPC1	-0.017851
CXorf23	-0.017840
TET2	-0.017836
PGAM2	-0.017809
LMNTD2	-0.017809
IGKV4-1	-0.017784
BCS1L	-0.017751
BARX1	-0.017711
CEP170	-0.017680
WRB	-0.017595
MAP7	-0.017577
TIA1	-0.017576
LINC00926	-0.017576
ZDHHC20	-0.017576
JOSD1	-0.017563
FAM43B	-0.017539
ABRACL	-0.017518