!direction	-1
!num_genes	281
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Rattus norvegicus
!drug_name	Caerulein
!smiles	CC(C(C(=O)NCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CCSC)C(=O)NC(CC(=O)O)C(=O)NC(CC3=CC=CC=C3)C(=O)N)NC(=O)C(CC4=CC=C(C=C4)OS(=O)(=O)O)NC(=O)C(CC(=O)O)NC(=O)C(CCC(=O)N)NC(=O)C5CCC(=O)N5)O
!pubchem_cid	16132921
!cell_type	Livers - 48 hours after exposure
!organism	rat
!end_metadata
INSIG1	-0.168846
COMT	-0.156161
SCD	-0.116712
ALAS1	-0.110206
UQCRQ	-0.100954
MIF	-0.098858
TUBB2A	-0.095642
ERRFI1	-0.090225
PCK1	-0.087816
METTL7B	-0.085541
HSD17B6	-0.082571
CHCHD10	-0.076482
CEBPB	-0.071229
RCAN1	-0.069109
RPL35	-0.068076
TSKU	-0.067836
RPL27A	-0.065788
RPL31	-0.063706
TAT	-0.063517
TXN	-0.061082
SEC61G	-0.060732
RPS17	-0.060728
RPS28	-0.058617
APOC4	-0.055846
RPS15	-0.053629
GAPDH	-0.052578
CALR	-0.051597
CREG1	-0.051521
P4HB	-0.051481
RPL38	-0.051282
ATP5J2	-0.050746
GSTK1	-0.050620
IRF2BP2	-0.050205
CA3	-0.049965
RPS12	-0.049811
PDIA4	-0.049168
RPL27	-0.049144
RPS26	-0.046437
RPS11	-0.045249
COX7A2	-0.045216
RPL37	-0.044868
FADS1	-0.044540
CYP1A2	-0.044364
JUND	-0.044107
SOD1	-0.043424
FABP5	-0.043262
GCK	-0.042671
RPS23	-0.042305
HSPA8	-0.042142
TSC22D3	-0.041370
NSDHL	-0.040322
ALDH9A1	-0.039764
RPS21	-0.039675
LONP2	-0.039500
PGPEP1	-0.039252
SERPINA6	-0.038999
ATP5A1	-0.038808
NDUFA11	-0.038461
GCKR	-0.037871
ACLY	-0.037779
APOC2	-0.037736
USMG5	-0.037495
UQCR10	-0.037451
AKR1A1	-0.037441
RPL19	-0.037407
NDUFB4	-0.037350
DAK	-0.037329
PSMB9	-0.037079
TTR	-0.037015
NDUFB11	-0.037004
COX1	-0.036911
MFGE8	-0.036881
RPS10	-0.036544
RPS3	-0.036503
IRF1	-0.036469
GUCD1	-0.036465
RPN1	-0.036217
WFDC2	-0.036083
HEBP1	-0.036080
RPS9	-0.035806
RTP4	-0.035711
NDRG2	-0.035461
ATOX1	-0.035238
DDAH1	-0.034792
HHEX	-0.034428
ATP5G1	-0.034391
RPL18	-0.034390
RPL7A	-0.034343
DDT	-0.034080
COX7B	-0.033787
PSMB3	-0.033704
ZNF354A	-0.033514
ROMO1	-0.033506
RPL15	-0.033387
FAU	-0.033373
FDPS	-0.033359
TOMM7	-0.033354
PPA1	-0.033273
PCSK9	-0.033231
MFSD2A	-0.033184
GRHPR	-0.033035
TST	-0.032889
NDUFB5	-0.032709
SEC61B	-0.032545
ENO1	-0.032503
SGK1	-0.032499
ALDH2	-0.032404
INSIG2	-0.032308
APOA2	-0.032279
TSPAN31	-0.032269
RPL12	-0.032068
SELK	-0.031892
RPS20	-0.031762
PKLR	-0.031751
PARK7	-0.031385
TMEM205	-0.030987
SULT2A1	-0.030907
COPE	-0.030827
ATP5B	-0.030810
IGFBP3	-0.030666
RPS16	-0.030662
RPL10A	-0.030436
NDUFB9	-0.030373
ACSL5	-0.030239
SOCS2	-0.030123
VKORC1	-0.029996
SURF4	-0.029990
RARRES2	-0.029927
LMAN2	-0.029780
HINT2	-0.029649
ETFB	-0.029344
KPNA2	-0.029028
HAL	-0.028994
CERS2	-0.028925
MANF	-0.028891
NDUFA4	-0.028480
TALDO1	-0.028455
RPS19	-0.028105
NDUFB2	-0.027997
TUBB4B	-0.027993
PPP1R3C	-0.027971
RPL28	-0.027562
MYEOV2	-0.027390
SLC39A4	-0.027280
NDUFB7	-0.027075
RPS29	-0.027055
GBE1	-0.026992
MOCS2	-0.026880
HAGH	-0.026820
HERPUD1	-0.026645
MID1IP1	-0.026319
GCHFR	-0.026184
PAH	-0.026102
AGMO	-0.026030
CES1	-0.025884
AGT	-0.025756
MST1	-0.025702
NDUFV3	-0.025641
TMA7	-0.025359
ATP5O	-0.025343
RNASEK	-0.025091
SORD	-0.025050
AMBP	-0.024962
MKNK2	-0.024955
FADS2	-0.024915
PSMB4	-0.024799
UBC	-0.024720
COX8A	-0.024536
LCMT1	-0.024525
SLC22A8	-0.024491
HSP90B1	-0.024473
APOM	-0.024456
ND2	-0.024452
TMEM256	-0.024317
NDUFA3	-0.024263
LYZ	-0.024218
GSTM5	-0.024214
ATP5H	-0.024148
DCAF11	-0.024110
MDH2	-0.024066
SNRPD2	-0.023879
ASS1	-0.023832
RPL11	-0.023687
AHSG	-0.023679
HSP90AB1	-0.023665
HSPA5	-0.023539
TMEM258	-0.023532
HAO1	-0.023513
TUBA4A	-0.023501
LDHA	-0.023331
IRF7	-0.023275
CDC42EP4	-0.023169
TKT	-0.023121
NDUFB6	-0.023112
MRPL54	-0.023107
KRT8	-0.023077
PDIA6	-0.023063
FKBP11	-0.023037
BCAP31	-0.022981
CD164	-0.022934
PSENEN	-0.022857
UGDH	-0.022856
POLR2L	-0.022809
IRF2BP1	-0.022785
SHMT2	-0.022727
OSGIN1	-0.022609
DBI	-0.022604
EPHX2	-0.022572
EDF1	-0.022427
RPL22	-0.022411
TGFBI	-0.022380
ADTRP	-0.022364
RAN	-0.022238
BDH1	-0.022211
COL3A1	-0.022204
PSMA7	-0.021962
CLPTM1L	-0.021801
EGR1	-0.021664
ARHGAP17	-0.021512
CLEC4F	-0.021477
RBP4	-0.021452
HSD3B7	-0.021450
PSME2	-0.021449
KDELR2	-0.021447
MGP	-0.021352
SIGMAR1	-0.021286
SLC38A2	-0.021252
ECHDC3	-0.021195
MIPEP	-0.021138
CNDP2	-0.021129
DNAJB11	-0.021118
VCP	-0.021097
GAS2	-0.021052
SV2B	-0.021004
VPS29	-0.020930
USE1	-0.020849
LAMTOR4	-0.020847
UBE2L6	-0.020801
SSR4	-0.020777
SPCS1	-0.020773
COX4I1	-0.020667
LY6E	-0.020538
CAPNS1	-0.020458
NDUFS8	-0.020452
DAD1	-0.020294
NUCB2	-0.020258
DYNLL1	-0.020143
APMAP	-0.020025
PPIB	-0.019975
RPS13	-0.019967
GPX1	-0.019896
RHOB	-0.019750
ATP6V0D1	-0.019748
MAGED1	-0.019655
HMGCR	-0.019443
MBL2	-0.019359
UQCRB	-0.019297
BLOC1S1	-0.019254
PMVK	-0.019218
RPL13A	-0.019157
RPS7	-0.019061
ATP5L	-0.019053
SERP1	-0.018971
HGD	-0.018943
CTDSP1	-0.018832
GSTA5	-0.018801
APOA1	-0.018662
MRPL41	-0.018579
ALAD	-0.018421
TMEM97	-0.018394
M6PR	-0.018382
SPCS2	-0.018373
CD14	-0.018336
FBP1	-0.018253
DNAJC22	-0.018160
CRELD2	-0.018117
UQCR11	-0.018028
CYC1	-0.017971
FECH	-0.017831
RPL9	-0.017762
DHRS3	-0.017756