!direction	-1
!num_genes	270
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Homo sapiens
!ligand_name	estradiol
!ligand_id	CHEBI:23965
!cell_type	endothelial cells
!organism	human
!end_metadata
MT2A	-0.182630
ND2	-0.127817
ITGA5	-0.111899
PFN1	-0.102860
IGFBP4	-0.099580
MT1X	-0.099450
RPS4Y1	-0.095072
SH3BGRL3	-0.090384
PODXL	-0.088072
MT1H	-0.083851
MT1HL1	-0.082785
TAGLN	-0.082092
BASP1	-0.073773
BGN	-0.072544
FLNA	-0.071224
HTRA1	-0.070006
PKD1P1	-0.068424
S100A6	-0.067485
MYL9	-0.065670
CD81	-0.064122
GSTP1	-0.063047
ZYX	-0.062151
HSPG2	-0.061765
PTPRO	-0.060249
TUBA1B	-0.060148
RPS26	-0.059144
TUBA1C	-0.058819
PPIB	-0.058621
LTBP2	-0.057837
SLC25A3	-0.057799
RPL36	-0.057722
COL4A2	-0.056404
GNG5	-0.055418
ICAM2	-0.054198
ACTN4	-0.053651
NPIPA1	-0.053105
ARHGDIA	-0.050956
DKK1	-0.049729
CHCHD2	-0.049511
MYH9	-0.048548
COL5A1	-0.048211
HLA-A	-0.048076
MIF	-0.047735
NPC2	-0.047672
ENG	-0.047429
GABARAP	-0.046892
S100A11	-0.046810
TUBB3	-0.046118
GPX1	-0.045848
COX6C	-0.045759
TIMP2	-0.045124
TTYH3	-0.045046
PPDPF	-0.044771
PLOD1	-0.043030
SNRPD2	-0.042263
CALR	-0.042236
CD151	-0.041854
CD9	-0.041748
GBE1	-0.041622
TSPO	-0.040877
PRKCSH	-0.040708
PEA15	-0.040520
TPM4	-0.040432
RPL19	-0.040381
SPATA20	-0.040285
FAU	-0.040064
TUBB4B	-0.039656
MVP	-0.039539
P4HB	-0.039521
VAT1	-0.039172
ABHD17A	-0.039001
HHIP	-0.038839
TMSB10	-0.038616
UQCRQ	-0.037928
CTHRC1	-0.037924
HMGA1	-0.037547
IFI6	-0.037416
HYAL2	-0.037065
GNB2	-0.036644
GNAI2	-0.036470
IGFBP2	-0.036084
ARF4	-0.036001
TUBA1A	-0.035804
OST4	-0.035783
FABP5	-0.035051
GPX4	-0.035022
PSMB6	-0.034735
FBLIM1	-0.034694
PSMB5	-0.034675
IL32	-0.034674
SPOCK1	-0.034294
FTH1	-0.034282
RTN4	-0.033347
S100A13	-0.033331
TRIM22	-0.033244
MT1E	-0.033021
PKM	-0.032986
NOP10	-0.032984
DENND5A	-0.032770
MCAM	-0.032743
TPI1	-0.032613
RCN1	-0.032593
ACTN1	-0.032452
PCBP1	-0.032140
ECHS1	-0.031706
ALDH2	-0.031687
FKBP1A	-0.031519
SGK1	-0.031251
YWHAE	-0.031204
GAS6	-0.031193
HIGD2A	-0.031132
TGFB1	-0.031130
PLXND1	-0.031002
HYI	-0.030971
DUSP23	-0.030555
EIF5A	-0.030550
GRINA	-0.029951
CTSB	-0.029940
NDUFA13	-0.029803
CAP1	-0.029784
TUBB6	-0.029187
ALCAM	-0.029107
TGFBI	-0.029084
IGFBP7	-0.029078
ITGA3	-0.029028
CD99	-0.028477
SOD1	-0.028193
PSMD8	-0.027975
HIST1H4C	-0.027807
CST3	-0.027618
ALDOA	-0.027335
RPL4	-0.027304
FSCN1	-0.027304
CLSTN1	-0.027163
FAM50A	-0.026804
MTCH1	-0.026782
EGFL7	-0.026649
PEBP1	-0.026597
CLIC1	-0.026534
LDHA	-0.026447
PLD3	-0.026415
TUBB2A	-0.026397
PRSS23	-0.026303
TAGLN2	-0.026274
PLOD2	-0.026077
FBLN5	-0.025964
HN1	-0.025951
TPM1	-0.025706
ECE1	-0.025577
NPDC1	-0.025473
SRGN	-0.025359
TALDO1	-0.025240
IRAK1	-0.025058
PTRF	-0.025004
RPS9	-0.025003
ROMO1	-0.024933
TUBB	-0.024595
LOXL2	-0.024556
MGLL	-0.024531
PLOD3	-0.024360
NME4	-0.024189
S100A10	-0.024148
ACTB	-0.024081
PIP5K1C	-0.023986
VPS51	-0.023943
LOC399491	-0.023810
DKK3	-0.023699
COX8A	-0.023599
TGFB1I1	-0.023449
CS	-0.023410
CLTA	-0.023296
TMEM147	-0.023278
DAD1	-0.023261
LAMTOR1	-0.023138
GARS	-0.023136
NDUFA12	-0.023125
PSMA1	-0.023106
SEMA3G	-0.023024
MAP7D1	-0.022972
CAPN2	-0.022892
SERPINH1	-0.022882
RHOB	-0.022819
RRAGA	-0.022796
ATP5E	-0.022759
MAGED2	-0.022417
RPS10	-0.022380
OSTC	-0.022376
HGS	-0.022297
APLP2	-0.022261
PPP1R14B	-0.022214
COX6A1	-0.022184
MYADM	-0.022174
EPB41L3	-0.022121
NDUFV2	-0.022107
MLLT11	-0.022092
ATP5B	-0.022017
SEP15	-0.021932
SHC1	-0.021930
VOPP1	-0.021864
PXDN	-0.021690
ZFAS1	-0.021642
TMEM258	-0.021284
CISD1	-0.021236
NDUFA3	-0.021226
EMP3	-0.021159
CFL1	-0.021141
NHP2	-0.021130
EDN1	-0.020910
FURIN	-0.020899
NPLOC4	-0.020810
STAB1	-0.020723
ILK	-0.020693
RRBP1	-0.020685
FCGRT	-0.020665
CCNI	-0.020592
ACVRL1	-0.020474
NTN4	-0.020438
EMC7	-0.020429
INHBA	-0.020385
TRAPPC1	-0.020356
FIBP	-0.020355
ESAM	-0.020352
VDAC2	-0.020306
CKAP4	-0.020219
PFKP	-0.020211
PLAT	-0.020157
SHISA5	-0.020067
MARCKS	-0.020021
UGCG	-0.019981
POLR2L	-0.019941
FAM127A	-0.019920
JAG2	-0.019901
LAMP1	-0.019861
ATP13A2	-0.019797
WASF2	-0.019787
LTBP1	-0.019778
EDF1	-0.019767
EIF6	-0.019697
RPL38	-0.019680
SEPN1	-0.019676
SLIRP	-0.019562
CD59	-0.019534
ISG15	-0.019417
FOLR1	-0.019331
YWHAG	-0.019235
YIF1A	-0.019183
SEC13	-0.019120
TP53I3	-0.019019
SEC31A	-0.018997
CDC42EP1	-0.018994
TRAPPC5	-0.018984
CYTL1	-0.018924
SDF4	-0.018886
GNB1	-0.018716
PKN1	-0.018597
MX1	-0.018565
ERH	-0.018347
PHPT1	-0.018199
ECSCR	-0.018170
VASP	-0.018115
ANKRD1	-0.018040
ATP6V0C	-0.017955
MAP1S	-0.017924
FKBP9	-0.017865
SELM	-0.017799
VIPR2	-0.017707
RPS27L	-0.017649
CDH2	-0.017529
NAP1L1	-0.017501
MAP4	-0.017442