!direction	-1
!num_genes	315
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	rat
!drug_name	NICKEL CHLORIDE
!smiles	Cl[Ni]Cl
!pubchem_cid	24385
!cell_type	H4-II-E-C3 LIVER-derived cell line - 140 uM
!organism	rat
!end_metadata
FABP1	-0.093926
ITIH4	-0.075692
AZGP1	-0.070640
LGALS2	-0.057099
SPSB2	-0.049968
TM4SF20	-0.047580
HDC	-0.046412
HAO1	-0.045687
ITIH2	-0.045382
ANGPTL3	-0.044538
C5	-0.044127
SCTR	-0.043970
OLFML3	-0.043941
PDZK1	-0.043932
SLC2A2	-0.043636
EHF	-0.041555
DDC	-0.041526
PIK3C2G	-0.040970
RGN	-0.040928
HMGCS2	-0.039533
SLC7A7	-0.039269
PON3	-0.039254
SPP2	-0.038494
BAAT	-0.038193
ALDH1B1	-0.037571
GLIPR1	-0.037507
DCXR	-0.036359
MYOF	-0.035692
SP2	-0.035263
ALDOB	-0.035116
IGFBPL1	-0.035000
FAM102B	-0.034696
PAQR8	-0.034670
SERPIND1	-0.034308
C8B	-0.034240
PPAP2B	-0.034196
APOBEC1	-0.033936
SLC13A4	-0.033773
DAPL1	-0.033360
SLC17A2	-0.033168
ASL	-0.032972
LPAR6	-0.032906
TGM2	-0.032508
XPNPEP2	-0.032441
PLA2G16	-0.032389
NME3	-0.032300
C9	-0.032262
ABCA4	-0.032246
CDH17	-0.032193
CDHR5	-0.032112
CRYAB	-0.031903
SEMA3C	-0.031691
LGALS1	-0.031633
SPPL2A	-0.031531
HSD17B13	-0.030881
MYRF	-0.030832
ANKRD44	-0.030818
QRICH2	-0.030756
SIGIRR	-0.030747
IL18	-0.030651
FETUB	-0.030620
UBE2L6	-0.030302
F10	-0.030260
LAMA3	-0.030090
ABCG5	-0.029971
SLCO1B3	-0.029953
MYLK	-0.029939
COL3A1	-0.029722
CPPED1	-0.029606
ITIH1	-0.029601
GLRX	-0.029564
LIG3	-0.029405
CLDN2	-0.029326
PPP1R36	-0.029323
ARHGEF26	-0.029148
CIDEC	-0.029000
AFP	-0.028952
PHLDB2	-0.028942
CAMKMT	-0.028800
SLC39A4	-0.028744
ACKR4	-0.028697
GNAQ	-0.028560
ALDH1A1	-0.028515
ZNF143	-0.028478
PTOV1	-0.028435
GALNT4	-0.028401
KMO	-0.028316
PLA2R1	-0.028250
SLC26A1	-0.028183
HRSP12	-0.028131
BCMO1	-0.028118
RNASE1	-0.028010
A2M	-0.027968
PLAC8	-0.027961
NCOA7	-0.027907
RABL3	-0.027875
FGA	-0.027729
RHPN2	-0.027658
COA4	-0.027602
RTP4	-0.027589
MGLL	-0.027535
COPS7A	-0.027488
ABCG8	-0.027384
LGALS9B	-0.027337
CALML4	-0.027293
ECI2	-0.027283
DIXDC1	-0.027274
UGCG	-0.027172
FBP1	-0.027104
CST6	-0.027084
CP	-0.027019
PHLDA2	-0.026840
TEN1	-0.026632
RAPGEF4	-0.026561
CLRN3	-0.026558
UAP1L1	-0.026379
GLOD5	-0.026343
PNPLA6	-0.026301
ACP2	-0.026171
LIMD2	-0.026162
CHDH	-0.026157
NMRK1	-0.026012
AMDHD2	-0.025948
MBL2	-0.025946
ANKS4B	-0.025739
PIK3AP1	-0.025668
FABP2	-0.025659
RHBDD1	-0.025612
ADPRH	-0.025577
TPMT	-0.025563
NAA38	-0.025484
MBOAT1	-0.025451
CLN3	-0.025437
ADAMTS4	-0.025427
TMEM50B	-0.025248
PHLDA1	-0.025186
SFXN5	-0.025183
SLC50A1	-0.025183
POC1B	-0.025168
MSH3	-0.025161
GJB1	-0.025153
CPB2	-0.025066
MST1	-0.024941
GDPD1	-0.024844
GALT	-0.024792
AS3MT	-0.024785
GAMT	-0.024756
CTH	-0.024564
PRDX4	-0.024549
VBP1	-0.024514
EXD2	-0.024491
RNASEK	-0.024411
CTSC	-0.024288
PLA1A	-0.024191
RUFY1	-0.024110
SH3GLB2	-0.024098
CD36	-0.024046
AQP8	-0.024026
BAX	-0.024022
NAAA	-0.023983
ABCA7	-0.023913
MET	-0.023887
KAZALD1	-0.023852
RFNG	-0.023780
KLHL41	-0.023735
ACADVL	-0.023722
TRAF3IP2	-0.023653
FGL1	-0.023620
RFX4	-0.023605
FLOT1	-0.023565
AKR1D1	-0.023533
CYP27A1	-0.023480
TCEAL1	-0.023420
VPS13B	-0.023403
DEPDC7	-0.023390
HGFAC	-0.023371
MANSC1	-0.023271
ISPD	-0.023218
MMP19	-0.023055
TMEM37	-0.023039
TTR	-0.023037
PROC	-0.023011
SLC25A21	-0.022950
SULT2A1	-0.022902
FASN	-0.022843
MYZAP	-0.022832
ID2	-0.022818
FAM171B	-0.022645
NEU2	-0.022630
APEH	-0.022583
NR1H4	-0.022577
ABCC6	-0.022559
SOX6	-0.022515
ACY1	-0.022497
GNAT3	-0.022475
PCTP	-0.022451
TRAPPC1	-0.022346
ALDH1L2	-0.022307
TGFBR2	-0.022273
ADTRP	-0.022238
SNAP29	-0.022165
ADHFE1	-0.022125
ARSA	-0.022107
SULT1B1	-0.022091
KDSR	-0.022079
TNFSF13	-0.022049
SLC23A1	-0.022026
C8G	-0.021936
RAMP2	-0.021898
PBLD	-0.021882
MAP2K6	-0.021875
F12	-0.021770
ABCA1	-0.021761
SPATA33	-0.021745
SLC52A3	-0.021617
HFE	-0.021542
DPP7	-0.021528
ZFP36	-0.021429
AK1	-0.021428
LRRC16A	-0.021349
CCNG1	-0.021333
KNG1	-0.021317
NEU3	-0.021305
ZCCHC9	-0.021212
ACY3	-0.021199
PSMB8	-0.021197
VIL1	-0.021155
IGSF5	-0.021136
PLCB1	-0.021119
LCAT	-0.021104
PFN2	-0.021100
SLC22A7	-0.021077
GULP1	-0.021063
GRB14	-0.021063
RAB32	-0.021054
PDZD11	-0.020966
ARSB	-0.020960
TLE6	-0.020959
DDAH1	-0.020941
HMHA1	-0.020937
TPRKB	-0.020882
NEIL1	-0.020863
PAPSS2	-0.020858
CPT2	-0.020848
TM6SF2	-0.020782
GUSB	-0.020679
OTUD3	-0.020643
SLC22A18	-0.020639
RETSAT	-0.020630
ZNF335	-0.020629
CYTH1	-0.020622
ANPEP	-0.020565
SH3BP5	-0.020499
CLCN7	-0.020478
UGT2B17	-0.020454
ELOVL6	-0.020453
PIDD	-0.020450
GPCPD1	-0.020438
NGEF	-0.020431
IFI44L	-0.020412
ST3GAL1	-0.020412
MGST3	-0.020397
GBA	-0.020382
ENPP2	-0.020352
SLC27A2	-0.020318
TMEM17	-0.020282
ABCB1	-0.020234
CORO6	-0.020230
F5	-0.020216
GPM6A	-0.020194
GSTZ1	-0.020188
ASPA	-0.020187
DPYD	-0.020181
TNFRSF9	-0.020169
VPS28	-0.020080
GSTM1	-0.020056
BSCL2	-0.020055
POMK	-0.020046
CFI	-0.020022
B3GAT3	-0.019996
SUOX	-0.019860
FMO5	-0.019791
LGALS3BP	-0.019763
ACOX3	-0.019702
SLC22A17	-0.019668
TIMELESS	-0.019651
NAGK	-0.019619
RAB3D	-0.019611
TFPI	-0.019607
PPP1R17	-0.019586
KCNG3	-0.019568
TXNDC16	-0.019562
CIDEB	-0.019558
LECT2	-0.019528
CNP	-0.019527
HEXA	-0.019519
TMEM256	-0.019515
GOLT1A	-0.019495
PALM	-0.019479
FAM171A1	-0.019472
GLUL	-0.019469
IL17RE	-0.019454
PKLR	-0.019438
MYO10	-0.019433
OLFML2A	-0.019397
GAS2	-0.019359
ADAM9	-0.019342
PDK2	-0.019337
ACOT1	-0.019322
SLC16A7	-0.019298
NPTX1	-0.019292
PPFIBP2	-0.019291
ITPR1	-0.019283
TIMM8B	-0.019277
DHTKD1	-0.019261