!direction	-1
!num_genes	300
!diffexp_method	chdir
!cutoff	500
!correction_method	None
!threshold	None
!organism	Mus musculus
!cell	heart
!perturbation	isocitrate dehydrogenase 2 R172K mutant
!disease	cardiomyopathy
!end_metadata
MB	-0.105659
ACTC1	-0.097598
MYOZ2	-0.091980
IFNGR2	-0.090660
ENO3	-0.086757
MYL7	-0.084001
MYL2	-0.083915
CCNG1	-0.075278
ETFB	-0.072226
COX7A1	-0.071847
CHRM2	-0.071212
LRRC10	-0.067783
ZNF106	-0.067242
TNNI3	-0.067112
CANX	-0.066275
GJA1	-0.065939
COX6A2	-0.064938
TNNT2	-0.063916
ANTXR2	-0.063354
RPL18A	-0.062814
CTSD	-0.062177
CES1	-0.062112
ABCC9	-0.061865
LGALS1	-0.060548
CLU	-0.060028
ATP2A2	-0.058395
PSME4	-0.056932
FSD2	-0.056779
CACNA2D1	-0.055170
OGN	-0.054837
HSP90AB1	-0.053542
RPLP0	-0.052442
CASQ1	-0.052330
DES	-0.051170
RPL3L	-0.050862
MDH2	-0.050719
TMEM50B	-0.049164
IVD	-0.047704
HSPA5	-0.046953
GSTK1	-0.046354
CLIP4	-0.046338
ATP1A2	-0.045046
NDUFB9	-0.044895
CDH2	-0.044671
HFE2	-0.044651
TTN	-0.044570
CSRP3	-0.044544
CHPT1	-0.044495
CD81	-0.043967
APOBEC2	-0.043770
EIF4G2	-0.042607
DPT	-0.042567
RYR2	-0.042407
NAMPT	-0.042337
FITM1	-0.042012
PIK3R1	-0.041866
DCN	-0.040476
LCLAT1	-0.040386
SLC16A1	-0.040112
MEF2A	-0.039218
SUMO2	-0.038811
IDH2	-0.038431
HSP90B1	-0.038375
MAT2A	-0.038284
LBH	-0.037923
SH3RF2	-0.037413
SSPN	-0.037350
IL13RA1	-0.037310
GHR	-0.037258
CRAT	-0.037229
FASTK	-0.037117
EGLN1	-0.036801
YIPF7	-0.036746
CS	-0.036693
ATF3	-0.036494
AS3MT	-0.036304
ACADM	-0.036177
COX20	-0.036118
BLOC1S1	-0.036103
SORD	-0.035345
MUT	-0.035329
SNAP23	-0.035217
PCDH7	-0.035179
CSDE1	-0.034389
IDH3G	-0.034049
PYGM	-0.033946
CDK2AP1	-0.033594
KCNJ3	-0.033462
CAMK2D	-0.033343
TFPI	-0.033236
ISCA1	-0.032859
CORIN	-0.032475
POLR2F	-0.032345
ASB14	-0.032211
ASB15	-0.031766
HOPX	-0.031682
NDUFV1	-0.031569
UBE2D3	-0.031441
NDRG2	-0.031430
CREG1	-0.031292
UBC	-0.030992
PFKM	-0.030932
GSTP1	-0.030725
REEP5	-0.030173
TUBA1B	-0.030071
DYNLRB1	-0.030059
ECHS1	-0.029972
RPS20	-0.029962
LPL	-0.029944
TMEM65	-0.029852
MYBPC3	-0.029679
RPL10A	-0.029613
PPT1	-0.029402
CRIP1	-0.029401
DUSP7	-0.029379
SYNGR2	-0.029350
PLBD1	-0.029341
DHDH	-0.029247
LMAN2	-0.029073
SMIM20	-0.029010
PPIF	-0.029009
ANGPTL2	-0.028946
USMG5	-0.028886
PFKFB2	-0.028808
MPV17	-0.028769
SDHC	-0.028638
SGCB	-0.028597
CALR	-0.028520
CHCHD3	-0.028018
NDUFB4	-0.027955
CCDC141	-0.027753
DSP	-0.027606
GPC1	-0.027591
COX7B	-0.027459
NUAK1	-0.027391
PHYH	-0.027232
HHATL	-0.027194
KCNJ5	-0.027091
WFS1	-0.026975
C10orf107	-0.026881
YBX1	-0.026724
AKR1B1	-0.026599
LAMP1	-0.026530
MID1IP1	-0.026121
GID4	-0.026032
DBT	-0.025984
IDH3B	-0.025942
ART3	-0.025928
UQCRQ	-0.025788
ATP5C1	-0.025787
NEXN	-0.025688
ADPRHL1	-0.025666
GBAS	-0.025652
SLC2A4	-0.025599
FH	-0.025562
ATG10	-0.025557
MYOCD	-0.025496
SAMM50	-0.025475
ACTG1	-0.025455
RPL18	-0.025396
PALLD	-0.025342
TMEM160	-0.025308
GRM1	-0.025274
WNK1	-0.025262
TMEM182	-0.025221
MRPS21	-0.025156
YAE1D1	-0.025136
PPP2R3A	-0.024981
TXN	-0.024822
ASNSD1	-0.024725
OTUD1	-0.024677
LMOD3	-0.024668
CAPNS1	-0.024596
GNA12	-0.024591
CYB5A	-0.024492
FYCO1	-0.024491
ATP5H	-0.024394
ISOC1	-0.024345
RFK	-0.024334
RALGAPA2	-0.024245
B2M	-0.024210
NDUFB5	-0.024140
NDUFS6	-0.024117
PINK1	-0.024018
HSPB8	-0.023979
HDLBP	-0.023951
LAMB2	-0.023669
CD164	-0.023611
EEF1A2	-0.023586
FBLN1	-0.023550
JUN	-0.023508
DGAT2	-0.023460
RAB10	-0.023088
AES	-0.023044
RPS6	-0.023014
NEO1	-0.023001
HSPB6	-0.022885
ANKH	-0.022876
GSN	-0.022824
BCHE	-0.022715
SGCA	-0.022701
TXLNB	-0.022642
ANAPC13	-0.022559
PSMB3	-0.022192
FMO1	-0.022162
PKIA	-0.021959
PPP1R14C	-0.021911
TMX4	-0.021903
RBM24	-0.021676
UQCR11	-0.021433
ENTPD4	-0.021419
RARB	-0.021182
RPS26	-0.021167
LRRC39	-0.021069
RPS15	-0.020862
MYL1	-0.020822
C3	-0.020800
ALDH2	-0.020752
CA3	-0.020716
YWHAE	-0.020698
TMX2	-0.020685
TANGO2	-0.020672
GSTM1	-0.020579
LRTM1	-0.020568
TMOD4	-0.020520
RPS5	-0.020486
LAPTM4A	-0.020216
CAP2	-0.020112
CLYBL	-0.019962
LAMP2	-0.019928
ACADSB	-0.019918
NRD1	-0.019907
SLC6A8	-0.019822
AGTPBP1	-0.019775
NDUFB11	-0.019768
KLHL41	-0.019765
SLC25A12	-0.019704
ATP5J2	-0.019685
ARL1	-0.019596
TMEM126A	-0.019555
BCAT2	-0.019537
RAB2A	-0.019468
RPL12	-0.019447
MYLK3	-0.019425
RBM20	-0.019416
GABARAP	-0.019367
HNRNPU	-0.019331
NDUFS1	-0.019320
APOE	-0.019220
CLASP1	-0.019168
MAOB	-0.019104
DAG1	-0.019101
UQCC2	-0.019082
BVES	-0.019062
SLC44A2	-0.018970
LDHA	-0.018832
FAU	-0.018801
KCNG2	-0.018773
BOD1	-0.018692
SLC20A2	-0.018675
GAS6	-0.018649
CTSC	-0.018644
PSMD7	-0.018512
NDUFB8	-0.018433
STARD10	-0.018406
ACTB	-0.018400
MYH7	-0.018277
SCN5A	-0.018277
MCEE	-0.018219
PRKRIR	-0.018148
GNPAT	-0.018140
NAA20	-0.018076
RAB21	-0.017979
HNRNPA2B1	-0.017943
LPIN1	-0.017925
GPR22	-0.017914
FUCA2	-0.017904
FAM96A	-0.017899
KIF5B	-0.017895
VEGFA	-0.017858
LSMEM1	-0.017822
TRIM63	-0.017821
HIPK2	-0.017687
RPL5	-0.017682
ASB2	-0.017626
IL6ST	-0.017625
ECHDC2	-0.017587
S100A1	-0.017538
PLA2G5	-0.017525
CUTA	-0.017508
ACAT1	-0.017496
IMMT	-0.017431
CDH13	-0.017396
QKI	-0.017336
ATP5G2	-0.017242
SFPQ	-0.017239
CST3	-0.017235
DDX5	-0.017187
LDHB	-0.017113
TRIM55	-0.017109